| Literature DB >> 22350336 |
Diana E Schendel1, Carolyn Diguiseppi, Lisa A Croen, M Daniele Fallin, Philip L Reed, Laura A Schieve, Lisa D Wiggins, Julie Daniels, Judith Grether, Susan E Levy, Lisa Miller, Craig Newschaffer, Jennifer Pinto-Martin, Cordelia Robinson, Gayle C Windham, Aimee Alexander, Arthur S Aylsworth, Pilar Bernal, Joseph D Bonner, Lisa Blaskey, Chyrise Bradley, Jack Collins, Casara J Ferretti, Homayoon Farzadegan, Ellen Giarelli, Marques Harvey, Susan Hepburn, Matthew Herr, Kristina Kaparich, Rebecca Landa, Li-Ching Lee, Brooke Levenseller, Stacey Meyerer, Mohammad H Rahbar, Andria Ratchford, Ann Reynolds, Steven Rosenberg, Julie Rusyniak, Stuart K Shapira, Karen Smith, Margaret Souders, Patrick Aaron Thompson, Lisa Young, Marshalyn Yeargin-Allsopp.
Abstract
The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal, gastrointestinal, and sociodemographic characteristics. SEED uses a case-control design with population-based ascertainment of children aged 2-5 years with an autism spectrum disorder (ASD) and children in two control groups-one from the general population and one with non-ASD developmental problems. Data from parent-completed questionnaires, interviews, clinical evaluations, biospecimen sampling, and medical record abstraction focus on the prenatal and early postnatal periods. SEED is a valuable resource for testing hypotheses regarding ASD characteristics and causes.Entities:
Mesh：
Year: 2012 PMID： 22350336 PMCID： PMC4455890 DOI： 10.1007/s10803-012-1461-8
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257