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Literature DB >> 22348705

The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks.

Tatiana V Morozova¹, David Goldman, Trudy F C Mackay, Robert R H Anholt.

Abstract

Alcoholism is a significant public health problem. A picture of the genetic architecture underlying alcohol-related phenotypes is emerging from genome-wide association studies and work on genetically tractable model organisms.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

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Year: 2012 PMID： 22348705 PMCID： PMC3334563 DOI： 10.1186/gb-2012-13-2-239

Source DB: PubMed Journal: Genome Biol ISSN： 1474-7596 Impact factor: 13.583

99 in total

1. Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men.

Authors: Inkyung Baik; Nam H Cho; Seong Hwan Kim; Bok-Ghee Han; Chol Shin
Journal: Am J Clin Nutr Date: 2011-01-26 Impact factor: 7.045

2. A genome-wide association study of alcohol dependence.

Authors: Laura J Bierut; Arpana Agrawal; Kathleen K Bucholz; Kimberly F Doheny; Cathy Laurie; Elizabeth Pugh; Sherri Fisher; Louis Fox; William Howells; Sarah Bertelsen; Anthony L Hinrichs; Laura Almasy; Naomi Breslau; Robert C Culverhouse; Danielle M Dick; Howard J Edenberg; Tatiana Foroud; Richard A Grucza; Dorothy Hatsukami; Victor Hesselbrock; Eric O Johnson; John Kramer; Robert F Krueger; Samuel Kuperman; Michael Lynskey; Karl Mann; Rosalind J Neuman; Markus M Nöthen; John I Nurnberger; Bernice Porjesz; Monika Ridinger; Nancy L Saccone; Scott F Saccone; Marc A Schuckit; Jay A Tischfield; Jen C Wang; Marcella Rietschel; Alison M Goate; John P Rice
Journal: Proc Natl Acad Sci U S A Date: 2010-03-02 Impact factor: 11.205

3. A serotonin transporter polymorphism (5-HTTLPR) predicts the development of adolescent alcohol use.

Authors: Carmen S van der Zwaluw; Rutger C M E Engels; Ad A Vermulst; Richard J Rose; Robbert J Verkes; Jan Buitelaar; Barbara Franke; Ron H J Scholte
Journal: Drug Alcohol Depend Date: 2010-07-03 Impact factor: 4.492

Review 4. A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models.

Authors: Cindy L Ehlers; Nicole A R Walter; Danielle M Dick; Kari J Buck; John C Crabbe
Journal: Addict Biol Date: 2010-04 Impact factor: 4.280

5. Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Authors: Howard J Edenberg; Daniel L Koller; Xiaoling Xuei; Leah Wetherill; Jeanette N McClintick; Laura Almasy; Laura J Bierut; Kathleen K Bucholz; Alison Goate; Fazil Aliev; Danielle Dick; Victor Hesselbrock; Anthony Hinrichs; John Kramer; Sam Kuperman; John I Nurnberger; John P Rice; Marc A Schuckit; Robert Taylor; B Todd Webb; Jay A Tischfield; Bernice Porjesz; Tatiana Foroud
Journal: Alcohol Clin Exp Res Date: 2010-03-01 Impact factor: 3.455

Review 6. GABA-B receptors in Drosophila.

Authors: Hari Manev; Svetlana Dzitoyeva
Journal: Adv Pharmacol Date: 2010

7. A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.

Authors: Penelope A Lind; Stuart Macgregor; Jacqueline M Vink; Michele L Pergadia; Narelle K Hansell; Marleen H M de Moor; August B Smit; Jouke-Jan Hottenga; Melinda M Richter; Andrew C Heath; Nicholas G Martin; Gonneke Willemsen; Eco J C de Geus; Nicole Vogelzangs; Brenda W Penninx; John B Whitfield; Grant W Montgomery; Dorret I Boomsma; Pamela A F Madden
Journal: Twin Res Hum Genet Date: 2010-02 Impact factor: 1.587

8. Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila.

Authors: Eric C Kong; Lorien Allouche; Paul A Chapot; Karen Vranizan; Monica S Moore; Ulrike Heberlein; Fred W Wolf
Journal: Alcohol Clin Exp Res Date: 2009-11-24 Impact factor: 3.455

9. Laboratory mouse models for the human genome-wide associations.

Authors: Georgios D Kitsios; Navdeep Tangri; Peter J Castaldi; John P A Ioannidis
Journal: PLoS One Date: 2010-11-01 Impact factor: 3.240

10. Ethanol preference in C. elegans.

Authors: J Lee; C Jee; S L McIntire
Journal: Genes Brain Behav Date: 2009-06-22 Impact factor: 3.449

22 in total

Review 1. Genetics of alcoholism.

Authors: Priya A Iyer-Eimerbrink; John I Nurnberger
Journal: Curr Psychiatry Rep Date: 2014-12 Impact factor: 5.285

Review 2. Closing the 'phenotype gap' in precision medicine: improving what we measure to understand complex disease mechanisms.

Authors: Calum A MacRae
Journal: Mamm Genome Date: 2019-08-19 Impact factor: 2.957

Review 3. Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder.

Authors: Mike Grotewiel; Jill C Bettinger
Journal: Alcohol Clin Exp Res Date: 2015-07-14 Impact factor: 3.455

4. Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population.

Authors: Maria Pombar-Gomez; Elixabet Lopez-Lopez; Idoia Martin-Guerrero; Africa Garcia-Orad Carles; Marian M de Pancorbo
Journal: Int J Legal Med Date: 2015-03-13 Impact factor: 2.686

Review 5. Genetic studies of alcohol dependence in the context of the addiction cycle.

Authors: Matthew T Reilly; Antonio Noronha; David Goldman; George F Koob
Journal: Neuropharmacology Date: 2017-01-22 Impact factor: 5.250

6. More than Meets the Eye: Eye Color and Alcoholism.

Authors: Joel C Eissenberg
Journal: Mo Med Date: 2016 Mar-Apr

7. A GABRA2 polymorphism improves a model for prediction of drinking initiation.

Authors: Samuel Kuperman; Grace Chan; John Kramer; Leah Wetherill; Laura Acion; Howard J Edenberg; Tatiana M Foroud; John Nurnberger; Arpana Agrawal; Andrey Anokhin; Andrew Brooks; Victor Hesselbrock; Michie Hesselbrock; Marc Schuckit; Jay Tischfield; Xiangtao Liu
Journal: Alcohol Date: 2017-06-28 Impact factor: 2.405

8. Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.

Authors: Jason A Bubier; Jeremy J Jay; Christopher L Baker; Susan E Bergeson; Hiroshi Ohno; Pamela Metten; John C Crabbe; Elissa J Chesler
Journal: Genetics Date: 2014-06-11 Impact factor: 4.562

9. Putative calcium-binding domains of the Caenorhabditis elegans BK channel are dispensable for intoxication and ethanol activation.

Authors: S J Davis; L L Scott; G Ordemann; A Philpo; J Cohn; J T Pierce-Shimomura
Journal: Genes Brain Behav Date: 2015-07 Impact factor: 3.449

10. Homosexual inclinations and the passions: A Thomistic theory of the psychogenesis of same-sex attraction disorder.

Authors: Robert Loyd Kinney
Journal: Linacre Q Date: 2014-05