Literature DB >> 22348471

NMDA receptors in immune competent cells.

A A Boldyrev1, E A Bryushkova, E A Vladychenskaya.   

Abstract

This review presents analysis of literature data indicating the presence of NMDA-type glutamate receptors in several types of immune competent cells such as thymocytes, lymphocytes, and neutrophils. The possible role of these receptors in the function of these cells is discussed. The interaction of the receptors with certain ligands circulating in the bloodstream and their role in modulation of immune function is described. It is suggested that homocysteine ​​acts as modulator of these receptors, and its toxicity is largely explained by hyperactivation of the NMDA-type glutamate receptors.

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Year:  2012        PMID： 22348471     DOI： 10.1134/S0006297912020022

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN： 0006-2979            Impact factor:   2.487


  16 in total

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Journal:  Pain Res Treat       Date:  2013-11-04

Review 9.  Glutamate receptor-like channels in plants: a role as amino acid sensors in plant defence?

Authors:  Brian G Forde; Michael R Roberts
Journal:  F1000Prime Rep       Date:  2014-06-02

Review 10.  NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

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Journal:  J Immunol Res       Date:  2016-05-12       Impact factor: 4.818
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