| Literature DB >> 22346551 |
Abstract
This review commemorates the 200th anniversary of Edward Jenner's development of a vaccine for variola, the cause of smallpox, and the 20th anniversary of its eradication. Jenner's original 23 case reports are briefly revisited within the context of earlier attempts to prevent this dreaded disease and in light of the current understanding of vaccinology and immunology. In addition, with molecular biological information available about many pox viruses and detailed sequence knowledge of some, it is now possible to appreciate Jenner's prescient accomplishments more fully.Entities:
Keywords: Edward Jenner; Pox viruses; Smallpox virus; Vaccination; Variolla
Year: 1998 PMID: 22346551 PMCID: PMC3250919 DOI: 10.1155/1998/390190
Source DB: PubMed Journal: Can J Infect Dis ISSN: 1180-2332