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Literature DB >> 22345603

James F. Crow and the stochastic theory of population genetics.

Abstract

Research in population genetics theory has two main strands. The first is deterministic theory, where random changes in allelic frequencies are ignored and attention focuses on the evolutionary effects of selection and mutation. The second strand, stochastic theory, takes account of these random changes and thus is more complete than deterministic theory. This essay is one in the series of Perspectives and Reviews honoring James F. Crow on the occasion of his 95th birthday. It concerns his contributions to, and involvement with, the stochastic theory of evolutionary population genetics.

Mesh：

Year: 2012 PMID： 22345603 PMCID： PMC3276629 DOI： 10.1534/genetics.111.135194

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

13 in total

James F. Crow and the stochastic theory of population genetics.

Review 1. Is Wright's shifting balance process important in evolution?

2. THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.

3. James F. Crow and the art of teaching and mentoring.

4. Role of very slightly deleterious mutations in molecular evolution and polymorphism.

5. On the meaning and existence of an effective population size.

6. Evolution in Mendelian Populations.

7. Is the most frequent allele the oldest?

8. The sampling theory of selectively neutral alleles.

9. The dilemma of nearly neutral mutations. How important are they for evolution and human welfare?

10. Theoretical foundation of population genetics at the molecular level.

1. Sewall Wright on Evolution in Mendelian Populations and the "Shifting Balance".

2. Motoo Kimura and James Crow on the Infinitely Many Alleles Model.