Literature DB >> 22345028

A novel HIV treatment model using private practitioners in South Africa.

Craig Innes1, Robin Hamilton, Christopher J Hoffmann, Piotr Hippner, Katherine Fielding, Alison D Grant, Gavin J Churchyard, Salome Charalambous.   

Abstract

OBJECTIVES: The extent of the HIV epidemic in South Africa may render the public sector capacity inadequate to manage all patients requiring antiretroviral treatment (ART). Private practitioners are an underutilised resource.
METHODS: The authors developed a model of care using 72 private practitioners in five provinces in urban and rural areas of South Africa with centralised clinical support, training, pharmacy control and data management. The authors describe the programme, its quality control measures and patient outcomes using a cohort analysis.
RESULTS: Between January 2005 and December 2008, 9102 individuals were started on ART, 62% female, median age 34 years, median viral load 50,655 copies/ml and median baseline CD4 count 123 cells/μl. Retention (alive and in care) after 12 months was 63% in the 2005 cohort (646 of 1026) and remained similar in the other calendar years, 58%, 68% and 64% in 2006, 2007 and 2008, respectively. After 36 months, retention was 50% and 41% for those enrolled in 2005 and 2006, respectively. The percentage virally suppressed remained similar at 6 months, 82% vs 84%, 84% and 85% from 2005, 2006, 2007 to 2008, respectively, p=0.66; but improved slightly at 12 months, 78% vs 83%, 83% and 84% from 2005 to 2008, p=0.05. At 36 months, it was 84% and 82% for the 2005 and 2006 cohorts, respectively.
CONCLUSIONS: The results show that a well-managed private practitioner model can achieve comparable results to public services, although long-term retention needs further evaluation. This model of ART delivery can be used to expand access to ART in areas where the public sector is unable to meet the demand.

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Year:  2012        PMID: 22345028      PMCID: PMC3724420          DOI: 10.1136/sextrans-2011-050194

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  15 in total

1.  Antiretroviral therapy in the private sector of Nairobi, Kenya: a review of the experience of five physicians.

Authors:  Doris K Macharia; Larry W Chang; Godfrey Lule; Dundu M Owili; Gebregiorgis Tesfaledet; Surendra Patel; David M Silverstein; Lucy Ng'ang'a; Tim Bush; Kevin M De Cock; Paul J Weidle
Journal:  AIDS       Date:  2003-04-11       Impact factor: 4.177

2.  Health systems and access to antiretroviral drugs for HIV in Southern Africa: service delivery and human resources challenges.

Authors:  Helen Schneider; Duane Blaauw; Lucy Gilson; Nzapfurundi Chabikuli; Jane Goudge
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Review 3.  The health and health system of South Africa: historical roots of current public health challenges.

Authors:  Hoosen Coovadia; Rachel Jewkes; Peter Barron; David Sanders; Diane McIntyre
Journal:  Lancet       Date:  2009-08-24       Impact factor: 79.321

4.  Sexually transmitted infections -- factors associated with quality of care among private general practitioners.

Authors:  H Schneider; N Chabikuli; D Blaauw; I Funani; R Brugha
Journal:  S Afr Med J       Date:  2005-10

Review 5.  Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: a systematic review.

Authors:  Roos E Barth; Maarten F Schim van der Loeff; Rob Schuurman; Andy I M Hoepelman; Annemarie M J Wensing
Journal:  Lancet Infect Dis       Date:  2010-03       Impact factor: 25.071

6.  Private practitioners and their role in the resurgence of malaria in Mumbai (Bombay) and Navi Mumbai (New Bombay), India: serving the affected or aiding an epidemic?

Authors:  V R Kamat
Journal:  Soc Sci Med       Date:  2001-03       Impact factor: 4.634

7.  Quality and equity of private sector care for sexually transmitted diseases in South Africa.

Authors:  Nzapfurundi Chabikuli; Helen Schneider; Duane Blaauw; Anthony B Zwi; Ruairí Brugha
Journal:  Health Policy Plan       Date:  2002-12       Impact factor: 3.344

8.  Effectiveness of highly active antiretroviral therapy administered by general practitioners in rural South Africa.

Authors:  R E Barth; J T M van der Meer; A I M Hoepelman; P A Schrooders; D A van de Vijver; S P M Geelen; H A Tempelman
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-07-16       Impact factor: 3.267

9.  Evaluation of a workplace HIV treatment programme in South Africa.

Authors:  Salome Charalambous; Craig Innes; Debbie Muirhead; Lilani Kumaranayake; Katherine Fielding; Lindiwe Pemba; Robin Hamilton; Alison Grant; Gavin J Churchyard
Journal:  AIDS       Date:  2007-07       Impact factor: 4.177

10.  Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysis.

Authors:  Gilles Van Cutsem; Nathan Ford; Katherine Hildebrand; Eric Goemaere; Shaheed Mathee; Musaed Abrahams; David Coetzee; Andrew Boulle
Journal:  PLoS One       Date:  2011-02-17       Impact factor: 3.240

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  13 in total

Review 1.  Retention of Adult Patients on Antiretroviral Therapy in Low- and Middle-Income Countries: Systematic Review and Meta-analysis 2008-2013.

Authors:  Matthew P Fox; Sydney Rosen
Journal:  J Acquir Immune Defic Syndr       Date:  2015-05-01       Impact factor: 3.731

2.  Patient satisfaction with HIV/AIDS care at private clinics in Dar es Salaam, Tanzania.

Authors:  James S Miller; Aisa Mhalu; Guerino Chalamilla; Hellen Siril; Silvia Kaaya; Justina Tito; Eric Aris; Lisa R Hirschhorn
Journal:  AIDS Care       Date:  2014-02-06

3.  Mortality associated with delays between clinic entry and ART initiation in resource-limited settings: results of a transition-state model.

Authors:  Christopher J Hoffmann; James J Lewis; David W Dowdy; Katherine L Fielding; Alison D Grant; Neil A Martinson; Gavin J Churchyard; Richard E Chaisson
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4.  Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa.

Authors:  Christopher J Hoffmann; Johanna Ledwaba; Jin-Fen Li; Victoria Johnston; Gillian Hunt; Katherine L Fielding; Richard E Chaisson; Gavin J Churchyard; Alison D Grant; Jeffrey A Johnson; Salome Charalambous; Lynn Morris
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5.  CD4 count-based failure criteria combined with viral load monitoring may trigger worse switch decisions than viral load monitoring alone.

Authors:  Christopher J Hoffmann; Jean Maritz; Gert U van Zyl
Journal:  Trop Med Int Health       Date:  2015-12-10       Impact factor: 2.622

6.  Treatment outcomes of HIV-positive patients on first-line antiretroviral therapy in private versus public HIV clinics in Johannesburg, South Africa.

Authors:  Faith Moyo; Charles Chasela; Alana T Brennan; Osman Ebrahim; Ian M Sanne; Lawrence Long; Denise Evans
Journal:  Clin Epidemiol       Date:  2016-03-18       Impact factor: 4.790

7.  Retention and mortality outcomes from a community-supported public-private HIV treatment programme in Myanmar.

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8.  Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.

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Journal:  PLoS One       Date:  2013-05-14       Impact factor: 3.240

9.  Viral suppression following switch to second-line antiretroviral therapy: associations with nucleoside reverse transcriptase inhibitor resistance and subtherapeutic drug concentrations prior to switch.

Authors:  Victoria Johnston; Karen Cohen; Lubbe Wiesner; Lynn Morris; Johanna Ledwaba; Katherine L Fielding; Salome Charalambous; Gavin Churchyard; Andrew Phillips; Alison D Grant
Journal:  J Infect Dis       Date:  2013-08-13       Impact factor: 5.226

10.  Insights of private general practitioners in group practice on the introduction of National Health Insurance in South Africa.

Authors:  Shabir Moosa; John Luiz; Teresa Carmichael; Wim Peersman; Anselme Derese
Journal:  Afr J Prim Health Care Fam Med       Date:  2016-06-15
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