OBJECTIVE: This study addresses if deficits in cognitive, attention, and inhibitory control performance in adults with ADHD are better explained by the disorder itself or by comorbid conditions. METHOD: Adult patients with ADHD (n = 352) and controls (n = 94) were evaluated in the ADHD program of a tertiary hospital. The diagnostic process for ADHD and comorbidities was based on Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) criteria. Stepwise regression analyses evaluated the effect of ADHD, demographics, and comorbidities on the scores from Wechsler Adult Intelligence Scale-Revised, Continuous Performance Test, and Stroop Color and Word Test. RESULTS: Patients with ADHD of both genders had worse performance on neuropsychological domains, even after adjustment for comorbidities. The presence of comorbid bipolar disorder and specific phobia are associated with more Stroop errors, whereas patients with generalized anxiety disorder present a longer execution time in Stroop. CONCLUSION: Neuropsychological deficits in adults with ADHD go beyond comorbidity. Specific comorbid disorders may influence the neuropsychological functioning in adults with ADHD.
OBJECTIVE: This study addresses if deficits in cognitive, attention, and inhibitory control performance in adults with ADHD are better explained by the disorder itself or by comorbid conditions. METHOD: Adult patients with ADHD (n = 352) and controls (n = 94) were evaluated in the ADHD program of a tertiary hospital. The diagnostic process for ADHD and comorbidities was based on Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) criteria. Stepwise regression analyses evaluated the effect of ADHD, demographics, and comorbidities on the scores from Wechsler Adult Intelligence Scale-Revised, Continuous Performance Test, and Stroop Color and Word Test. RESULTS:Patients with ADHD of both genders had worse performance on neuropsychological domains, even after adjustment for comorbidities. The presence of comorbid bipolar disorder and specific phobia are associated with more Stroop errors, whereas patients with generalized anxiety disorder present a longer execution time in Stroop. CONCLUSION: Neuropsychological deficits in adults with ADHD go beyond comorbidity. Specific comorbid disorders may influence the neuropsychological functioning in adults with ADHD.
Entities:
Keywords:
ADHD; adults; attention; cognition; comorbidity; inhibitory control
Authors: Jeanette C Mostert; Martine Hoogman; A Marten H Onnink; Daan van Rooij; Daniel von Rhein; Kimm J E van Hulzen; Janneke Dammers; Cornelis C Kan; Jan K Buitelaar; David G Norris; Barbara Franke Journal: J Atten Disord Date: 2015-09-14 Impact factor: 3.256
Authors: Jeanette C Mostert; A Marten H Onnink; Barbara Franke; Martine Hoogman; Marieke Klein; Janneke Dammers; Anais Harneit; Theresa Schulten; Kimm J E van Hulzen; Cornelis C Kan; Dorine Slaats-Willemse; Jan K Buitelaar Journal: Eur Neuropsychopharmacol Date: 2015-08-21 Impact factor: 4.600
Authors: Thomas Dresler; Beatrix Barth; Thomas Ethofer; Klaus-Peter Lesch; Ann-Christine Ehlis; Andreas J Fallgatter Journal: Borderline Personal Disord Emot Dysregul Date: 2014-05-12