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Literature DB >> 22337135

Cellular transport and homeostasis of essential and nonessential metals.

Ebany J Martinez-Finley¹, Sudipta Chakraborty, Stephanie J B Fretham, Michael Aschner.

Abstract

Metals can have a number of detrimental or beneficial effects in the cell, but first they must get in. Organisms have evolved transport mechanisms to get metals that are required, or essential into the cell. Nonessential metals often enter the cell through use of the machinery provided for essential metals. Much work has been done to advance our understanding of how these metals are transported across plasma and organelle membranes. This review provides an overview of essential and nonessential metal transport and homeostatic processes.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Metals

Year: 2012 PMID： 22337135 PMCID： PMC4936191 DOI： 10.1039/c2mt00185c

Source DB: PubMed Journal: Metallomics ISSN： 1756-5901 Impact factor: 4.526

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