Literature DB >> 22334819

Epidemic vitamin D deficiency among patients in an elderly care rehabilitation facility.

Stefan Schilling1.   

Abstract

BACKGROUND: Many benefits are ascribed to vitamin D beyond its well-known effects on calcium and bone metabolism. Vitamin D in adequate amounts is apparently beneficial to muscle, lessening the risk of falls and fractures in the elderly. The elderly produce less vitamin D in their skin than younger persons do, and they also spend less time in the sun; they are therefore at greater risk of vitamin D deficiency.
METHODS: We used gas chromatography with mass spectrometry coupling to measure the 25-OH-vitamin D level of 1578 elderly persons (72% women) who were consecutively admitted to an elderly care rehabilitation facility in Trier, Germany, from July 2009 to March 2011. Their mean and median age was 82 years.
RESULTS: 89% of the patients had 25-OH-vitamin D deficiency (defined as a level below 20 ng/mL), and 67% had a severe deficiency (below 10 ng/mL). Only 4% had levels in the target range (30-60 ng/mL); none had a level above 100 ng/mL.
CONCLUSION: Many of these patients were deficient in vitamin D. Persons of very advanced age need a better supply of vitamin D not only to keep their bones healthy, but also to lessen the risk of falls and fractures.

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Year:  2012        PMID: 22334819      PMCID: PMC3272588          DOI: 10.3238/arztebl.2012.0033

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  29 in total

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Journal:  N Engl J Med       Date:  2007-07-19       Impact factor: 91.245

2.  Vitamin D concentrations among people aged 65 years and over living in private households and institutions in England: population survey.

Authors:  Vasant Hirani; Paola Primatesta
Journal:  Age Ageing       Date:  2005-07-25       Impact factor: 10.668

3.  Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women.

Authors:  M Pfeifer; B Begerow; H W Minne; D Nachtigall; C Hansen
Journal:  J Clin Endocrinol Metab       Date:  2001-04       Impact factor: 5.958

Review 4.  Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications.

Authors:  P Lips
Journal:  Endocr Rev       Date:  2001-08       Impact factor: 19.871

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Authors:  M F Holick
Journal:  Am J Clin Nutr       Date:  1995-03       Impact factor: 7.045

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Authors:  Michal L Melamed; Erin D Michos; Wendy Post; Brad Astor
Journal:  Arch Intern Med       Date:  2008-08-11

Review 7.  Vitamin D deficiency: a worldwide problem with health consequences.

Authors:  Michael F Holick; Tai C Chen
Journal:  Am J Clin Nutr       Date:  2008-04       Impact factor: 7.045

8.  Vitamin D status and health correlates among German adults.

Authors:  B Hintzpeter; G B M Mensink; W Thierfelder; M J Müller; C Scheidt-Nave
Journal:  Eur J Clin Nutr       Date:  2007-05-30       Impact factor: 4.016

9.  Higher prevalence of vitamin D deficiency is associated with immigrant background among children and adolescents in Germany.

Authors:  Birte Hintzpeter; Christa Scheidt-Nave; Manfred J Müller; Liane Schenk; Gert B M Mensink
Journal:  J Nutr       Date:  2008-08       Impact factor: 4.798

Review 10.  Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials.

Authors:  Heike A Bischoff-Ferrari; Walter C Willett; John B Wong; Andreas E Stuck; Hannes B Staehelin; E John Orav; Anna Thoma; Douglas P Kiel; Jana Henschkowski
Journal:  Arch Intern Med       Date:  2009-03-23
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  20 in total

1.  Correspondence (letter to the editor): Appeal for vitamin D therapy.

Authors:  Stefan Pilz; Andreas Tomaschitz; Katharina Kienreich; Astrid Fahrleitner-Pammer; Winfried März
Journal:  Dtsch Arztebl Int       Date:  2012-05-11       Impact factor: 5.594

2.  Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients.

Authors:  Debbie L Matossian-Motley; Diane A Drake; John S Samimi; Carlos A Camargo; Sadeq A Quraishi
Journal:  JPEN J Parenter Enteral Nutr       Date:  2014-10-14       Impact factor: 4.016

3.  [Calcium and vitamin D in osteology].

Authors:  M Amling; F Barvencik
Journal:  Z Rheumatol       Date:  2015-06       Impact factor: 1.372

4.  Vitamin D metabolites and fibroblast growth factor-23 in patients with left ventricular assist device implants: association with stroke and mortality risk.

Authors:  A Zittermann; M Morshuis; J Kuhn; S Pilz; J B Ernst; C Oezpeker; J Dreier; C Knabbe; J F Gummert; H Milting
Journal:  Eur J Nutr       Date:  2015-02-06       Impact factor: 5.614

Review 5.  Is vitamin D deficiency a major global public health problem?

Authors:  Cristina Palacios; Lilliana Gonzalez
Journal:  J Steroid Biochem Mol Biol       Date:  2013-11-12       Impact factor: 4.292

6.  Is there an epidemic vitamin D deficiency in German orthopaedic patients?

Authors:  Gerrit Steffen Maier; Philipp Jakobs; Klaus Edgar Roth; Andreas Alois Kurth; Uwe Maus
Journal:  Clin Orthop Relat Res       Date:  2013-04-23       Impact factor: 4.176

7.  Vitamin D insufficiency in the elderly orthopaedic patient: an epidemic phenomenon.

Authors:  Gerrit Steffen Maier; Konstantin Horas; Jörn Bengt Seeger; Klaus Edgar Roth; Andreas Alois Kurth; Uwe Maus
Journal:  Int Orthop       Date:  2014-09-10       Impact factor: 3.075

Review 8.  [Calcium and vitamin D in bone metabolism: Clinical importance for fracture treatment].

Authors:  M Amling
Journal:  Unfallchirurg       Date:  2015-12       Impact factor: 1.000

9.  Serum concentrations of 25-hydroxyvitamin D and immunoglobulins in an older Swiss cohort: results of the Senior Labor Study.

Authors:  Benjamin Sakem; Cristina Nock; Zeno Stanga; Pedro Medina; Urs E Nydegger; Martin Risch; Lorenz Risch
Journal:  BMC Med       Date:  2013-08-01       Impact factor: 8.775

10.  Vitamin D status among adults in Germany--results from the German Health Interview and Examination Survey for Adults (DEGS1).

Authors:  Martina Rabenberg; Christa Scheidt-Nave; Markus A Busch; Nina Rieckmann; Birte Hintzpeter; Gert B M Mensink
Journal:  BMC Public Health       Date:  2015-07-11       Impact factor: 3.295

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