Literature DB >> 23609810

Is there an epidemic vitamin D deficiency in German orthopaedic patients?

Gerrit Steffen Maier1, Philipp Jakobs, Klaus Edgar Roth, Andreas Alois Kurth, Uwe Maus.   

Abstract

BACKGROUND: Vitamin D plays an essential role in bone health and muscle function. Some studies have shown a widespread rate of vitamin D deficiency in the general population, but few have reported on the vitamin D status of orthopaedic patients. QUESTIONS/PURPOSES: We investigated (1) the extent of hypovitaminosis D in orthopaedic patients, (2) seasonal variations in vitamin D levels, and (3) possible risk factors for insufficient vitamin D levels.
METHODS: Vitamin D levels in 1119 patients consecutively admitted to an orthopaedic surgery department in 2011 were measured. To investigate the correlation between climate factors and vitamin D levels, the sunshine hours for each month in 2011 were collected by Deutscher Wetterdienst (the German weather service) in the region where most tested patients lived. The prevalence of normal (> 30 ng/mL), insufficient (20-30 ng/mL), and deficient (< 20 ng/mL) 25-hydroxyvitamin D levels was determined. Univariate and multivariate analyses were used to assess risk factors for insufficient vitamin D levels.
RESULTS: Overall, 84% of patients had insufficient levels of vitamin D and 60% were vitamin D deficient. Only 15% were in the target range of 30 to 60 ng/mL. The prevalence of low vitamin D levels was greater during winter and months with fewer sunshine hours. Vitamin D levels did not vary according to age, sex, and disease. Individuals with obesity, hypertension, and osteoporosis were more likely to have low vitamin D levels compared with their healthy counterparts.
CONCLUSIONS: There is an alarmingly high rate of hypovitaminosis D and vitamin D deficiency among orthopaedic patients in this region of Germany, whose latitude (50° N) is approximately the same as those of Vancouver (49°, 15' N) and Paris (48°, 51' N). Given the well-known effects on bone metabolism and muscle health, low vitamin D levels may negatively affect patients. Screening and treating hypovitaminosis D appears to be important in this patient population.

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Year:  2013        PMID: 23609810      PMCID: PMC3734399          DOI: 10.1007/s11999-013-2996-5

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  41 in total

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Journal:  N Engl J Med       Date:  2007-07-19       Impact factor: 91.245

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Journal:  Arch Dermatol       Date:  1988-12

Review 4.  Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications.

Authors:  P Lips
Journal:  Endocr Rev       Date:  2001-08       Impact factor: 19.871

5.  High prevalence of vitamin D deficiency, secondary hyperparathyroidism and generalized bone pain in Turkish immigrants in Germany: identification of risk factors.

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Journal:  Osteoporos Int       Date:  2006-05-23       Impact factor: 4.507

6.  A randomized controlled trial of vitamin D3 supplementation for the prevention of symptomatic upper respiratory tract infections.

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Journal:  Epidemiol Infect       Date:  2009-03-19       Impact factor: 2.451

7.  Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study.

Authors:  K Holvik; H E Meyer; E Haug; L Brunvand
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8.  Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort.

Authors:  Tom R Hill; Alice A Cotter; Sarah Mitchell; Colin A Boreham; Werner Dubitzky; Liam Murray; J J Strain; Albert Flynn; Paula J Robson; Julie M W Wallace; Mairead Kiely; Kevin D Cashman
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9.  Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004.

Authors:  Anne C Looker; Christine M Pfeiffer; David A Lacher; Rosemary L Schleicher; Mary Frances Picciano; Elizabeth A Yetley
Journal:  Am J Clin Nutr       Date:  2008-12       Impact factor: 7.045

Review 10.  Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials.

Authors:  H A Bischoff-Ferrari; B Dawson-Hughes; H B Staehelin; J E Orav; A E Stuck; R Theiler; J B Wong; A Egli; D P Kiel; J Henschkowski
Journal:  BMJ       Date:  2009-10-01
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7.  Vitamin D deficiency in early implant failure: two case reports.

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8.  Sub-optimal serum 25-hydroxyvitamin D level affects 2-year survival after hip fracture surgery.

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9.  High prevalence and seasonal variation of hypovitaminosis D in patients scheduled for lower extremity total joint arthroplasty.

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10.  Is there an association between low serum 25-OH-D levels and the length of hospital stay in orthopaedic patients after arthroplasty?

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