Literature DB >> 22334240

Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines.

Masanari Takahashi1, Yasushi Takemoto, Tadahiro Shimazu, Hisashi Kawasaki, Makoto Tachibana, Yoichi Shinkai, Motoki Takagi, Kazuo Shin-ya, Yasuhiro Igarashi, Akihiro Ito, Minoru Yoshida.   

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Year:  2012        PMID： 22334240     DOI： 10.1038/ja.2012.6

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


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  7 in total

1.  Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases.

Authors:  Fanny L Cherblanc; Kathryn L Chapman; Robert Brown; Matthew J Fuchter
Journal:  Nat Chem Biol       Date:  2013-03       Impact factor: 15.040

2.  General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.

Authors:  John E DeLorbe; David Horne; Richard Jove; Steven M Mennen; Sangkil Nam; Fang-Li Zhang; Larry E Overman
Journal:  J Am Chem Soc       Date:  2013-03-01       Impact factor: 15.419

3.  Concise Total Synthesis of (+)-Luteoalbusins A and B.

Authors:  Timothy C Adams; Joshua N Payette; Jaime H Cheah; Mohammad Movassaghi
Journal:  Org Lett       Date:  2015-08-25       Impact factor: 6.005

4.  The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure.

Authors:  Tomohiko Ono; Naomi Kamimura; Tomohiro Matsuhashi; Toshihiro Nagai; Takahiko Nishiyama; Jin Endo; Takako Hishiki; Tsuyoshi Nakanishi; Noriaki Shimizu; Hirotoshi Tanaka; Shigeo Ohta; Makoto Suematsu; Masaki Ieda; Motoaki Sano; Keiichi Fukuda; Ruri Kaneda
Journal:  Sci Rep       Date:  2017-01-04       Impact factor: 4.379

Review 5.  Double the Chemistry, Double the Fun: Structural Diversity and Biological Activity of Marine-Derived Diketopiperazine Dimers.

Authors:  Nelson G M Gomes; Renato B Pereira; Paula B Andrade; Patrícia Valentão
Journal:  Mar Drugs       Date:  2019-09-27       Impact factor: 5.118

6.  Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically.

Authors:  Jan G Felber; Lena Poczka; Karoline C Scholzen; Lukas Zeisel; Martin S Maier; Sander Busker; Ulrike Theisen; Christina Brandstädter; Katja Becker; Elias S J Arnér; Julia Thorn-Seshold; Oliver Thorn-Seshold
Journal:  Nat Commun       Date:  2022-04-01       Impact factor: 14.919

7.  Novel pharmacological maps of protein lysine methyltransferases: key for target deorphanization.

Authors:  Obdulia Rabal; Andrea Castellar; Julen Oyarzabal
Journal:  J Cheminform       Date:  2018-07-21       Impact factor: 5.514
  7 in total

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