BACKGROUND: Little is known about HIV-1 subtype distribution in Morocco. Some data suggest an emergence of new HIV subtypes. We conducted phylogenetic analysis on a nationally representative sample of 60 HIV-1 viral specimens collected during 2004-2005 through the Morocco national HIV sentinel surveillance survey. RESULTS: While subtype B is still the most prevalent, 23.3% of samples represented non-B subtypes, the majority of which were classified as CRF02_AG (15%). Molecular clock analysis confirmed that the initial introduction of HIV-1B in Morocco probably came from Europe in the early 1980s. In contrast, the CRF02_AG strain appeared to be introduced from sub-Saharan Africa in two separate events in the 1990s. CONCLUSIONS: Subtype CRF02_AG has been emerging in Morocco since the 1990s. More information about the factors introducing HIV subtype-specific transmission will inform the prevention strategy in the region.
BACKGROUND: Little is known about HIV-1 subtype distribution in Morocco. Some data suggest an emergence of new HIV subtypes. We conducted phylogenetic analysis on a nationally representative sample of 60 HIV-1 viral specimens collected during 2004-2005 through the Morocco national HIV sentinel surveillance survey. RESULTS: While subtype B is still the most prevalent, 23.3% of samples represented non-B subtypes, the majority of which were classified as CRF02_AG (15%). Molecular clock analysis confirmed that the initial introduction of HIV-1B in Morocco probably came from Europe in the early 1980s. In contrast, the CRF02_AG strain appeared to be introduced from sub-Saharan Africa in two separate events in the 1990s. CONCLUSIONS: Subtype CRF02_AG has been emerging in Morocco since the 1990s. More information about the factors introducing HIV subtype-specific transmission will inform the prevention strategy in the region.
Authors: D L Robertson; J P Anderson; J A Bradac; J K Carr; B Foley; R K Funkhouser; F Gao; B H Hahn; M L Kalish; C Kuiken; G H Learn; T Leitner; F McCutchan; S Osmanov; M Peeters; D Pieniazek; M Salminen; P M Sharp; S Wolinsky; B Korber Journal: Science Date: 2000-04-07 Impact factor: 47.728
Authors: E Elharti; M Alami; H Khattabi; A Bennani; A Zidouh; A Benjouad; R El Aouad Journal: East Mediterr Health J Date: 2002-11 Impact factor: 1.628
Authors: F Simon; P Mauclère; P Roques; I Loussert-Ajaka; M C Müller-Trutwin; S Saragosti; M C Georges-Courbot; F Barré-Sinoussi; F Brun-Vézinet Journal: Nat Med Date: 1998-09 Impact factor: 53.440
Authors: Zhili Hu; Yingjie Liu; Jibao Wang; Zhefeng Meng; Sequoia I Leuba; Jie Wei; Xing Duan; Zhenxing Chu; Min Chen; Hong Shang; Junjie Xu Journal: Front Med (Lausanne) Date: 2022-04-27
Authors: S P Kouyoumjian; G R Mumtaz; N Hilmi; A Zidouh; H El Rhilani; K Alami; A Bennani; E Gouws; P D Ghys; L J Abu-Raddad Journal: Int J STD AIDS Date: 2013-07 Impact factor: 1.359