Literature DB >> 22332843

Neaumycin: a new macrolide from Streptomyces sp. NEAU-x211.

Sheng-Xiong Huang1, Xiang-Jing Wang, Yijun Yan, Ji-Dong Wang, Ji Zhang, Chong-Xi Liu, Wen-Sheng Xiang, Ben Shen.   

Abstract

Neaumycin, a new 30-membered macrolide featuring an internal diester bridge, a molecular architecture that is unprecedented among known macrolide natural products, was isolated from a soil actinomycete strain Streptomyces sp. NEAU-x211. The structure of neaumycin was elucidated on the basis of comprehensive mass and NMR spectroscopic interpretation, including the relative stereochemistry of four independent coupling systems.
© 2012 American Chemical Society

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22332843      PMCID： PMC3293494          DOI： 10.1021/ol300074d

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  17 in total

1.  Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

Authors:  Yinggang Luo; Wenli Li; Jianhua Ju; Qiuping Yuan; Noel R Peters; F Michael Hoffmann; Sheng-Xiong Huang; Tim S Bugni; Scott Rajski; Hiroyuki Osada; Ben Shen
Journal:  J Am Chem Soc       Date:  2010-05-19       Impact factor: 15.419

Review 2.  Current approaches to exploit actinomycetes as a source of novel natural products.

Authors:  Olga Genilloud; Ignacio González; Oscar Salazar; Jesus Martín; José Rubén Tormo; Francisca Vicente
Journal:  J Ind Microbiol Biotechnol       Date:  2010-10-08       Impact factor: 3.346

Review 3.  Bioactive microbial metabolites.

Authors:  János Bérdy
Journal:  J Antibiot (Tokyo)       Date:  2005-01       Impact factor: 2.649

Review 4.  Microbial genomics for the improvement of natural product discovery.

Authors:  Steven G Van Lanen; Ben Shen
Journal:  Curr Opin Microbiol       Date:  2006-05-02       Impact factor: 7.934

5.  Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600.

Authors:  Li-Xing Zhao; Sheng-Xiong Huang; Shu-Kun Tang; Cheng-Lin Jiang; Yanwen Duan; John A Beutler; Curtis J Henrich; James B McMahon; Tobias Schmid; Johanna S Blees; Nancy H Colburn; Scott R Rajski; Ben Shen
Journal:  J Nat Prod       Date:  2011-08-26       Impact factor: 4.050

6.  Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.

Authors:  Ian Paterson; Stephen M Dalby; Jill C Roberts; Guy J Naylor; Esther A Guzmán; Richard Isbrucker; Tara P Pitts; Pat Linley; Daniela Divlianska; John K Reed; Amy E Wright
Journal:  Angew Chem Int Ed Engl       Date:  2011-03-04       Impact factor: 15.336

7.  Stereochemistry of hexenyl radical cyclizations with tert-butyl and related large groups: substituent and temperature effects.

Authors:  Jonathan C Tripp; Carl H Schiesser; Dennis P Curran
Journal:  J Am Chem Soc       Date:  2005-04-20       Impact factor: 15.419

8.  Stereochemical Determination of Acyclic Structures Based on Carbon-Proton Spin-Coupling Constants. A Method of Configuration Analysis for Natural Products.

Authors:  Nobuaki Matsumori; Daisuke Kaneno; Michio Murata; Hideshi Nakamura; Kazuo Tachibana
Journal:  J Org Chem       Date:  1999-02-05       Impact factor: 4.354

9.  Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase.

Authors:  Zhiguo Yu; Sanja Vodanovic-Jankovic; Nathan Ledeboer; Sheng-Xiong Huang; Scott R Rajski; Michael Kron; Ben Shen
Journal:  Org Lett       Date:  2011-03-15       Impact factor: 6.005

10.  Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum.

Authors:  Dirk Menche; Fatih Arikan; Olena Perlova; Nicole Horstmann; Wiebke Ahlbrecht; Silke C Wenzel; Rolf Jansen; Herbert Irschik; Rolf Müller
Journal:  J Am Chem Soc       Date:  2008-10-01       Impact factor: 15.419
View more
  4 in total

1.  Additional congeners of the macrolide neaumycin: structure revision and biological activity.

Authors:  Matteo Simone; Sonia I Maffioli; Arianna Tocchetti; Stefano Tretter; Monica Cattaneo; Ida Biunno; Eleonora Gaspari; Stefano Donadio
Journal:  J Antibiot (Tokyo)       Date:  2015-01-14       Impact factor: 2.649

2.  New isofuranonaphthoquinones and isoindolequinones from Streptomyces sp. CB01883.

Authors:  Zhikai Guo; Guohui Pan; Zhengren Xu; Dong Yang; Xiangcheng Zhu; Yong Huang; Li-Xing Zhao; Yi Jiang; Yanwen Duan; Ben Shen
Journal:  J Antibiot (Tokyo)       Date:  2016-10-12       Impact factor: 2.649

3.  Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis.

Authors:  Ashootosh Tripathi; Michael M Schofield; George E Chlipala; Pamela J Schultz; Isaiah Yim; Sean A Newmister; Tyler D Nusca; Jamie B Scaglione; Philip C Hanna; Giselle Tamayo-Castillo; David H Sherman
Journal:  J Am Chem Soc       Date:  2014-01-17       Impact factor: 15.419

4.  Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora.

Authors:  Min Cheol Kim; Henrique Machado; Kyoung Hwa Jang; Lynnie Trzoss; Paul R Jensen; William Fenical
Journal:  J Am Chem Soc       Date:  2018-08-20       Impact factor: 15.419
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.