OBJECTIVES: Treatment regimens, which predictably support re-osseointegration of implants with peri-implantitis, are needed. Increased wettability may be an important factor for re-osseointegration. In this study, a cold atmospheric pressure gas-discharge plasma was applied to reduce water contact angles on titanium discs with different surface topography and to improve the spreading of osteoblastic cells. MATERIAL AND METHODS: An argon plasma jet with different oxygen admixtures was used to treat titanium discs with different topologies, i.e. machined, SLA(®) , SLActive(®) , diamond bur-treated or Airflow(®) -treated. Water contact angles were measured before and after plasma treatment. The spreading behaviour of human osteoblastic cells was investigated. RESULTS: Contact angle of titanium discs (baseline values: 68°-117°) were significantly reduced close to 0° irrespective of surface topography after the application of argon plasma with 1.0% oxygen admixture for 60 s or 120 s. The cell size of osteoblastic cells grown on argon-oxygen-plasma-treated titanium discs was significantly larger than on non-treated surfaces (p < 0.001) irrespective of surface topography. CONCLUSIONS: Plasma treatment reduced contact angle and supported spreading of osteoblastic cells. The application of cold plasma may be supportive in the treatment of peri-implant lesions and may improve the process of re-osseointegration.
OBJECTIVES: Treatment regimens, which predictably support re-osseointegration of implants with peri-implantitis, are needed. Increased wettability may be an important factor for re-osseointegration. In this study, a cold atmospheric pressure gas-discharge plasma was applied to reduce water contact angles on titanium discs with different surface topography and to improve the spreading of osteoblastic cells. MATERIAL AND METHODS: An argon plasma jet with different oxygen admixtures was used to treat titanium discs with different topologies, i.e. machined, SLA(®) , SLActive(®) , diamond bur-treated or Airflow(®) -treated. Water contact angles were measured before and after plasma treatment. The spreading behaviour of human osteoblastic cells was investigated. RESULTS: Contact angle of titanium discs (baseline values: 68°-117°) were significantly reduced close to 0° irrespective of surface topography after the application of argon plasma with 1.0% oxygen admixture for 60 s or 120 s. The cell size of osteoblastic cells grown on argon-oxygen-plasma-treated titanium discs was significantly larger than on non-treated surfaces (p < 0.001) irrespective of surface topography. CONCLUSIONS: Plasma treatment reduced contact angle and supported spreading of osteoblastic cells. The application of cold plasma may be supportive in the treatment of peri-implant lesions and may improve the process of re-osseointegration.
Authors: Frank Rupp; Rolando A Gittens; Lutz Scheideler; Abraham Marmur; Barbara D Boyan; Zvi Schwartz; Jürgen Geis-Gerstorfer Journal: Acta Biomater Date: 2014-02-28 Impact factor: 8.947
Authors: Rolando A Gittens; Lutz Scheideler; Frank Rupp; Sharon L Hyzy; Jürgen Geis-Gerstorfer; Zvi Schwartz; Barbara D Boyan Journal: Acta Biomater Date: 2014-04-05 Impact factor: 8.947
Authors: Marcel F Kunrath; André L M Vargas; Patrícia Sesterheim; Eduardo R Teixeira; Roberto Hubler Journal: J R Soc Interface Date: 2020-09-30 Impact factor: 4.118
Authors: Fernando P S Guastaldi; Daniel Yoo; Charles Marin; Ryo Jimbo; Nick Tovar; Darceny Zanetta-Barbosa; Paulo G Coelho Journal: Int J Biomater Date: 2013-01-10