Literature DB >> 22322360

Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3 + 2] cycloaddition.

Yaojia Jiang1, Vanessa Zhong Yue Khong, Emmanuvel Lourdusamy, Cheol-Min Park.   

Abstract

An efficient dual synthetic manifold for 2-aminofurans and 2-unsubstituted furans has been developed. The carbenoid-mediated [3 + 2] cycloaddition of copper carbenoids with enamines provides 2-amino-2,3-dihydrofurans which serve as common intermediates for both 2-aminofurans and 2-unsubstituted furans.

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Year:  2012        PMID: 22322360     DOI: 10.1039/c2cc18139h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Pyridazine N-Oxides as Precursors to 2-Aminofurans: Scope and Limitations in Complexity Building Cascade Reactions.

Authors:  Maribel Borger; James H Frederich
Journal:  Org Lett       Date:  2019-03-22       Impact factor: 6.072

2.  Bis-Rhodamines Bridged with a Diazoketone Linker: Synthesis, Structure, and Photolysis.

Authors:  Heydar Shojaei; Mariano L Bossi; Vladimir N Belov; Stefan W Hell
Journal:  J Org Chem       Date:  2021-12-17       Impact factor: 4.354

3.  Catalytic (3 + 2) annulation of donor-acceptor aminocyclopropane monoesters and indoles.

Authors:  Vincent Pirenne; Emma G L Robert; Jerome Waser
Journal:  Chem Sci       Date:  2021-05-05       Impact factor: 9.825

  3 in total

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