Literature DB >> 22318502

Functional status and health-related quality of life among allogeneic transplant patients at hospital discharge: a comparison of sociodemographic, disease, and treatment characteristics.

Marcia Grant1, Liz Cooke, Anna Cathy Williams, Smita Bhatia, Leslie Popplewell, Gwen Uman, Stephen Forman.   

Abstract

PURPOSE: The purpose of this paper is to report the findings of a study of hematopoietic cell transplant patients, describing the needs of allogeneic transplant patients at the time of discharge in regard to their functional status, quality of life (QOL), and caregiver information and comparing these needs across a number of sociodemographic, disease, and treatment characteristics. The findings of this study are part of a larger mixed-methods study, representing one data time point of the larger study.
METHODS: This paper will discuss the baseline data collected at the time of discharge for 282 allogeneic transplant patients, which include sociodemographic data combined with disease, treatment, functional status, and QOL data to present a comprehensive portrait of the transplant patient at discharge.
RESULTS: Mean age was 48 years, males represented 52%, and 22% of the patients were Hispanic. The majority of the patients had acute leukemia (55%), were diagnosed within the last 3 years, and had matched unrelated (52%) transplants. The time from transplant to discharge averaged 30 days. Mean scores for QOL (scale = 1-10, with 10 = best QOL) included a low score of 5.7 for both psychological and social well-being, 6.3 for overall QOL, and 7.1 for both physical and spiritual well-being. Males had significantly higher QOL than females, as did non-Hispanics. Patients with Hodgkin's disease had significantly lower overall QOL scores.
CONCLUSIONS: Our results highlight the physical, psychological, social, and spiritual challenges which present for patients and their caregivers at the time of hospital discharge following allogeneic transplant.

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Year:  2012        PMID: 22318502      PMCID: PMC3393810          DOI: 10.1007/s00520-012-1389-8

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  32 in total

1.  An EBMT registry matched study of allogeneic stem cell transplants for lymphoma: allogeneic transplantation is associated with a lower relapse rate but a higher procedure-related mortality rate than autologous transplantation.

Authors:  A J Peniket; M C Ruiz de Elvira; G Taghipour; C Cordonnier; E Gluckman; T de Witte; G Santini; D Blaise; H Greinix; A Ferrant; J Cornelissen; N Schmitz; A H Goldstone
Journal:  Bone Marrow Transplant       Date:  2003-04       Impact factor: 5.483

2.  Measurement of quality of life in bone marrow transplantation survivors.

Authors:  M Grant; B Ferrell; G M Schmidt; P Fonbuena; J C Niland; S J Forman
Journal:  Qual Life Res       Date:  1992-12       Impact factor: 4.147

3.  Gender-associated differences in the quality of life after allogeneic BMT.

Authors:  H Heinonen; L Volin; A Uutela; M Zevon; C Barrick; T Ruutu
Journal:  Bone Marrow Transplant       Date:  2001-09       Impact factor: 5.483

4.  Nurses' perceptions of the meaning of quality of life for bone marrow transplant survivors.

Authors:  C R King; B R Ferrell; M Grant; C Sakurai
Journal:  Cancer Nurs       Date:  1995-04       Impact factor: 2.592

Review 5.  Informal caregivers of hematopoietic cell transplant patients: a review and recommendations for interventions and research.

Authors:  Robin Gemmill; Liz Cooke; Anna Cathy Williams; Marcia Grant
Journal:  Cancer Nurs       Date:  2011 Nov-Dec       Impact factor: 2.592

6.  Quality of life immediately after peripheral blood stem cell transplantation.

Authors:  Eileen Danaher Hacker; Carol Estwing Ferrans
Journal:  Cancer Nurs       Date:  2003-08       Impact factor: 2.592

7.  The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs.

Authors:  C A McHorney; J E Ware; A E Raczek
Journal:  Med Care       Date:  1993-03       Impact factor: 2.983

8.  Psychometric study of quality of life instruments used during hospitalization for stem cell transplantation.

Authors:  Jesús M Prieto; Jorge Atala; Jordi Blanch; Enric Carreras; Montserrat Rovira; Esteve Cirera; Cristóbal Gastó
Journal:  J Psychosom Res       Date:  2004-08       Impact factor: 3.006

9.  Recovery and long-term function after hematopoietic cell transplantation for leukemia or lymphoma.

Authors:  Karen L Syrjala; Shelby L Langer; Janet R Abrams; Barry Storer; Jean E Sanders; Mary E D Flowers; Paul J Martin
Journal:  JAMA       Date:  2004-05-19       Impact factor: 56.272

10.  Psychosocial adjustment and quality of life among multiple myeloma patients undergoing evaluation for autologous stem cell transplantation.

Authors:  A C Sherman; S Simonton; U Latif; R Spohn; G Tricot
Journal:  Bone Marrow Transplant       Date:  2004-05       Impact factor: 5.483

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  3 in total

Review 1.  Sex, age, race and intervention type in clinical studies of HIV cure: a systematic review.

Authors:  Rowena E Johnston; Mary M Heitzeg
Journal:  AIDS Res Hum Retroviruses       Date:  2015-01       Impact factor: 2.205

2.  Quality of life of chronic myeloid leukemia patients in Brazil: ability to work as a key factor.

Authors:  Nelson Hamerschlak; Carmino de Souza; Ana Lúcia Cornacchioni; Ricardo Pasquini; Daniel Tabak; Nelson Spector; Merula Steagall
Journal:  Support Care Cancer       Date:  2014-03-20       Impact factor: 3.603

3.  Health-related quality of life of children and adolescents after hematopoietic stem cell transplantationa.

Authors:  Yu Min Hwang; Kyung-Sook Bang
Journal:  Child Health Nurs Res       Date:  2020-10-31
  3 in total

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