Literature DB >> 22310124

Unique pattern of complications in elderly trauma patients at a Level I trauma center.

Sasha D Adams1, Bryan A Cotton, Mary F McGuire, Edmundo Dipasupil, Jeanette M Podbielski, Adrian Zaharia, Drue N Ware, Brijesh S Gill, Rondel Albarado, Rosemary A Kozar, James R Duke, Philip R Adams, Carmel B Dyer, John B Holcomb.   

Abstract

BACKGROUND: Trauma centers are caring for increased proportions of elderly patients. Although age and Injury Severity Score are independently associated with mortality, trauma centers were originally designed to care for seriously injured patients without age-specific guidelines. We hypothesized that elderly patients would have different complication patterns than their younger counterparts.
METHODS: The trauma registry of an American College of Surgeons -verified Level I trauma center was queried for all patients older than 14 years admitted between January 2005 and December 2008. Mechanism, mortality, and complications were evaluated after dividing patients into eight age groups.
RESULTS: Of the 15,223 patients, 13% were elderly (≥65), and 86% were injured via a blunt mechanism. Increasing age correlated with fatality (all Injury Severity Scores), end-organ failure, and thromboembolic complications (deep venous thrombosis and coagulopathy). Analysis revealed a significant breakpoint at 45 years of age for mortality, decubitus ulcer, and renal failure (all p values <0.05). Infectious complications (sepsis, wound infection, and abscess) all peaked between 45 years and 65 years and then declined with increasing age.
CONCLUSIONS: We document that elderly trauma patients suffer the same complications as their younger counterparts, albeit at a different rate. More importantly, we identified a "breakpoint" of increased risk of complications and mortality at greater than 45 years. Although the mechanisms behind these observations remain unknown, understanding their unique patterns may allow appropriate allocation of resources and focus research efforts on interventions that should improve outcomes.

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Year:  2012        PMID: 22310124      PMCID: PMC3836632          DOI: 10.1097/TA.0b013e318241f073

Source DB:  PubMed          Journal:  J Trauma Acute Care Surg        ISSN: 2163-0755            Impact factor:   3.313


  19 in total

Review 1.  Practice management guidelines for geriatric trauma: the EAST Practice Management Guidelines Work Group.

Authors:  David G Jacobs; Brian Ray Plaisier; Philip S Barie; Jeffrey S Hammond; Michele R Holevar; Karlene E Sinclair; Thomas M Scalea; Wendy Wahl
Journal:  J Trauma       Date:  2003-02

2.  Definitions for sepsis and organ failure.

Authors:  R C Bone; C L Sprung; W J Sibbald
Journal:  Crit Care Med       Date:  1992-06       Impact factor: 7.598

Review 3.  American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.

Authors: 
Journal:  Crit Care Med       Date:  1992-06       Impact factor: 7.598

4.  Blunt trauma resuscitation: the old can respond.

Authors:  B A McKinley; R G Marvin; C S Cocanour; A Marquez; D N Ware; F A Moore
Journal:  Arch Surg       Date:  2000-06

5.  Impact of pediatric trauma centers on mortality in a statewide system.

Authors:  D A Potoka; L C Schall; M J Gardner; P W Stafford; A B Peitzman; H R Ford
Journal:  J Trauma       Date:  2000-08

6.  Multiple organ dysfunction during resuscitation is not postinjury multiple organ failure.

Authors:  David J Ciesla; Ernest E Moore; Jeffrey L Johnson; Angela Sauaia; Clay C Cothren; John B Moore; Jon M Burch
Journal:  Arch Surg       Date:  2004-06

Review 7.  Special considerations in geriatric injury.

Authors:  David G Jacobs
Journal:  Curr Opin Crit Care       Date:  2003-12       Impact factor: 3.687

8.  Morbidity from rib fractures increases after age 45.

Authors:  John B Holcomb; Neil R McMullin; Rosemary A Kozar; Marjorie H Lygas; Frederick A Moore
Journal:  J Am Coll Surg       Date:  2003-04       Impact factor: 6.113

9.  Trauma in the elderly: intensive care unit resource use and outcome.

Authors:  Michelle D Taylor; J Kathleen Tracy; Walter Meyer; Michael Pasquale; Lena M Napolitano
Journal:  J Trauma       Date:  2002-09

10.  In harm's way: Moving the older trauma patient toward a better outcome.

Authors:  James W Campbell; Peter A Degolia; William F Fallon; Erin L Rader
Journal:  Geriatrics       Date:  2009-01
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  26 in total

Review 1.  Injury in the aged: Geriatric trauma care at the crossroads.

Authors:  Rosemary A Kozar; Saman Arbabi; Deborah M Stein; Steven R Shackford; Robert D Barraco; Walter L Biffl; Karen J Brasel; Zara Cooper; Samir M Fakhry; David Livingston; Frederick Moore; Fred Luchette
Journal:  J Trauma Acute Care Surg       Date:  2015-06       Impact factor: 3.313

2.  Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma.

Authors:  Khalid Almahmoud; Rami A Namas; Othman Abdul-Malak; Akram M Zaaqoq; Ruben Zamora; Brian S Zuckerbraun; Jason Sperry; Andrew B Peitzman; Timothy R Billiar; Yoram Vodovotz
Journal:  Shock       Date:  2015-08       Impact factor: 3.454

3.  A simple clinical risk nomogram to predict mortality-associated geriatric complications in severely injured geriatric patients.

Authors:  Lillian Min; Sigrid Burruss; Eric Morley; Lona Mody; Jonathan R Hiatt; Henry Cryer; Jin-Kyung Ha; Areti Tillou
Journal:  J Trauma Acute Care Surg       Date:  2013-04       Impact factor: 3.313

4.  Older Adults With Isolated Rib Fractures Do Not Require Routine Intensive Care Unit Admission.

Authors:  Jessica A Bowman; Gregory J Jurkovich; Daniel K Nishijima; Garth H Utter
Journal:  J Surg Res       Date:  2019-08-22       Impact factor: 2.192

5.  Evaluation of major trauma in elderly patients - a single trauma center analysis.

Authors:  Samo Kocuvan; Drago Brilej; Domen Stropnik; Rolf Lefering; Radko Komadina
Journal:  Wien Klin Wochenschr       Date:  2016-11-28       Impact factor: 1.704

Review 6.  Practical Management of Anaesthesia in the Elderly.

Authors:  Camilla Strøm; Lars Simon Rasmussen; Jacob Steinmetz
Journal:  Drugs Aging       Date:  2016-11       Impact factor: 3.923

7.  Complications in low-risk older adult trauma patients: A case-control study.

Authors:  Robert A Tessler; Melissa M Rangel; Micaela L Rosser; Frederick P Rivara; Eileen Bulger; Monica S Vavilala; May J Reed; Saman Arbabi
Journal:  J Trauma Acute Care Surg       Date:  2019-05       Impact factor: 3.313

8.  Age and preexisting conditions as risk factors for severe adverse events and failure to rescue after injury.

Authors:  Emily Earl-Royal; Elinore J Kaufman; Jesse Y Hsu; Douglas J Wiebe; Patrick M Reilly; Daniel N Holena
Journal:  J Surg Res       Date:  2016-07-05       Impact factor: 2.192

Review 9.  Impact of age on the clinical outcomes of major trauma.

Authors:  F Hildebrand; H-C Pape; K Horst; H Andruszkow; P Kobbe; T-P Simon; G Marx; T Schürholz
Journal:  Eur J Trauma Emerg Surg       Date:  2015-08-08       Impact factor: 3.693

10.  Do not resuscitate status, not age, affects outcomes after injury: an evaluation of 15,227 consecutive trauma patients.

Authors:  Sasha D Adams; Bryan A Cotton; Charles E Wade; Rosemary A Kozar; Edmundo Dipasupil; Jeanette M Podbielski; Brijesh S Gill; James R Duke; Philip R Adams; John B Holcomb
Journal:  J Trauma Acute Care Surg       Date:  2013-05       Impact factor: 3.313

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