BACKGROUND: Salivary levels of Bifidobacteria have been shown to be significantly correlated with caries experience in adults but not as yet in children. HYPOTHESIS: Salivary levels of Bifidobacteria are positively associated with caries experience in children. AIM: To compare the salivary concentrations of Bifidobacteria of caries-free and caries-active children. DESIGN: Saliva was collected using the tongue-loop method from 38 caries-active children and from 22 clinically caries-free children, and the numbers of Bifidobacteria, mutans streptococci, lactobacilli and yeasts were determined. Additionally, the age and gender of the children, a plaque index, sugar amount in diet, sugar frequency in diet, hygiene practice and fluoride toothpaste usage were recorded. RESULTS: Bifidobacteria were isolated from 95% of the caries-active children and from only 9% of the caries-free children (P < 0.001). Salivary levels of Bifidobacteria were significantly correlated with amount of sugar in the diet, frequency of sugar consumption and oral hygiene practice. The significant variables that discriminated between the caries-free and caries-active subjects were salivary levels of Bifidobacteria, salivary levels of mutans streptococci and oral hygiene practice (χ(2) = 72.57, P < 0.001) and overall 90.0% of cases were correctly classified. CONCLUSIONS: Salivary levels of Bifidobacteria are significantly associated with caries experience in children. The salivary levels of this genus may be a useful marker of caries risk.
BACKGROUND: Salivary levels of Bifidobacteria have been shown to be significantly correlated with caries experience in adults but not as yet in children. HYPOTHESIS: Salivary levels of Bifidobacteria are positively associated with caries experience in children. AIM: To compare the salivary concentrations of Bifidobacteria of caries-free and caries-active children. DESIGN: Saliva was collected using the tongue-loop method from 38 caries-active children and from 22 clinically caries-free children, and the numbers of Bifidobacteria, mutans streptococci, lactobacilli and yeasts were determined. Additionally, the age and gender of the children, a plaque index, sugar amount in diet, sugar frequency in diet, hygiene practice and fluoride toothpaste usage were recorded. RESULTS: Bifidobacteria were isolated from 95% of the caries-active children and from only 9% of the caries-free children (P < 0.001). Salivary levels of Bifidobacteria were significantly correlated with amount of sugar in the diet, frequency of sugar consumption and oral hygiene practice. The significant variables that discriminated between the caries-free and caries-active subjects were salivary levels of Bifidobacteria, salivary levels of mutans streptococci and oral hygiene practice (χ(2) = 72.57, P < 0.001) and overall 90.0% of cases were correctly classified. CONCLUSIONS: Salivary levels of Bifidobacteria are significantly associated with caries experience in children. The salivary levels of this genus may be a useful marker of caries risk.
Authors: Jeffrey A Banas; Min Zhu; Deborah V Dawson; Derek R Blanchette; David R Drake; Hongjie Gu; Ryan Frost; Grant McCaulley; Steven M Levy Journal: J Oral Microbiol Date: 2016-10-26 Impact factor: 5.474
Authors: Lídia Audrey Rocha Valadas; Mariana Fernandes Gurgel; Joelma Martins Mororó; Said Gonçalves da Cruz Fonseca; Cristiane Sá Roriz Fonteles; Cibele Barreto Mano de Carvalho; Francisco Vagnaldo Fechine; Edilson Martins Rodrigues Neto; Marta Maria de França Fonteles; Francineudo Oliveira Chagas; Patrícia Leal Dantas Lobo; Mary Anne Medeiros Bandeira Journal: Saudi Pharm J Date: 2018-12-15 Impact factor: 4.330