Literature DB >> 22307979

Sulfonimidamides as sulfonamides bioisosteres: rational evaluation through synthetic, in vitro, and in vivo studies with γ-secretase inhibitors.

Fernando Sehgelmeble1, Juliette Janson, Colin Ray, Susanne Rosqvist, Susanne Gustavsson, Linda I Nilsson, Alexander Minidis, Jörg Holenz, Didier Rotticci, Johan Lundkvist, Per I Arvidsson.   

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Year:  2012        PMID： 22307979     DOI： 10.1002/cmdc.201200014

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  8 in total

1.  Saccharin Aza Bioisosteres-Synthesis and Preclinical Property Comparisons.

Authors:  Yantao Chen; Carl-Johan Aurell; Anna Pettersen; Richard J Lewis; Martin A Hayes; Matti Lepistö; Anna C Jonson; Hanna Leek; Linda Thunberg
Journal:  ACS Med Chem Lett       Date:  2017-05-01       Impact factor: 4.345

2.  Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic Acid bioisostere.

Authors:  Nils Pemberton; Henrik Graden; Emma Evertsson; Emma Bratt; Matti Lepistö; Petra Johannesson; Per H Svensson
Journal:  ACS Med Chem Lett       Date:  2012-05-30       Impact factor: 4.345

3.  Modular Two-Step Route to Sulfondiimidamides.

Authors:  Ze-Xin Zhang; Charles Bell; Mingyan Ding; Michael C Willis
Journal:  J Am Chem Soc       Date:  2022-06-21       Impact factor: 16.383

4.  Exploiting Configurational Lability in Aza-Sulfur Compounds for the Organocatalytic Enantioselective Synthesis of Sulfonimidamides.

Authors:  Michael J Tilby; Damien F Dewez; Adrian Hall; Carolina Martínez Lamenca; Michael C Willis
Journal:  Angew Chem Int Ed Engl       Date:  2021-11-02       Impact factor: 16.823

5.  A Silyl Sulfinylamine Reagent Enables the Modular Synthesis of Sulfonimidamides via Primary Sulfinamides.

Authors:  Mingyan Ding; Ze-Xin Zhang; Thomas Q Davies; Michael C Willis
Journal:  Org Lett       Date:  2022-02-21       Impact factor: 6.072

6.  Accessing Perfluoroaryl Sulfonimidamides and Sulfoximines via Photogenerated Perfluoroaryl Nitrenes: Synthesis and Application as a Chiral Auxiliary.

Authors:  Giampiero Proietti; Julius Kuzmin; Azamat Z Temerdashev; Peter Dinér
Journal:  J Org Chem       Date:  2021-11-12       Impact factor: 4.354

7.  Exploration of Novel Chemical Space: Synthesis and in vitro Evaluation of N-Functionalized Tertiary Sulfonimidamides.

Authors:  Flavia Izzo; Martina Schäfer; Philip Lienau; Ursula Ganzer; Robert Stockman; Ulrich Lücking
Journal:  Chemistry       Date:  2018-06-19       Impact factor: 5.236

8.  Harnessing Sulfinyl Nitrenes: A Unified One-Pot Synthesis of Sulfoximines and Sulfonimidamides.

Authors:  Thomas Q Davies; Michael J Tilby; Jack Ren; Nicholas A Parker; David Skolc; Adrian Hall; Fernanda Duarte; Michael C Willis
Journal:  J Am Chem Soc       Date:  2020-08-25       Impact factor: 15.419
  8 in total

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