Literature DB >> 22307203

An aptamer based on-plate microarray for high-throughput insulin detection by MALDI-TOF MS.

Xueyang Zhang1, Shaochun Zhu, Chunhui Deng, Xiangmin Zhang.   

Abstract

An aptamer microarray was directly fabricated on a MALDI target plate for high-throughput insulin detection. High sensitivities were observed both in standard solutions (5 ng mL(-1), 0.86 nM) and serum sample (20 ng mL(-1), 3.4 nM). This method shows great promise in the field of biomarker detection. This journal is © The Royal Society of Chemistry 2012

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Year:  2012        PMID: 22307203     DOI: 10.1039/c2cc17997k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Trends in the Design and Development of Specific Aptamers Against Peptides and Proteins.

Authors:  Maryam Tabarzad; Marzieh Jafari
Journal:  Protein J       Date:  2016-04       Impact factor: 2.371

Review 2.  Microarrays for identifying binding sites and probing structure of RNAs.

Authors:  Ryszard Kierzek; Douglas H Turner; Elzbieta Kierzek
Journal:  Nucleic Acids Res       Date:  2014-12-12       Impact factor: 16.971

3.  Immune-enrichment of insulin in bio-fluids on gold-nanoparticle decorated target plate and in situ detection by MALDI MS.

Authors:  Kai Liang; Hongmei Wu; Yan Li
Journal:  Clin Proteomics       Date:  2017-01-19       Impact factor: 3.988

4.  Sensitive colorimetric assay using insulin G-quadruplex aptamer arrays on DNA nanotubes coupled with magnetic nanoparticles.

Authors:  A Rafati; A Zarrabi; S Abediankenari; M Aarabi; P Gill
Journal:  R Soc Open Sci       Date:  2018-03-21       Impact factor: 2.963

  4 in total

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