| Literature DB >> 22305582 |
Hiroshi Imagawa1, Hayato Saijo, Hitomi Yamaguchi, Ken Maekawa, Takahiro Kurisaki, Hirofumi Yamamoto, Mugio Nishizawa, Masataka Oda, Michiko Kabura, Masahiro Nagahama, Jun Sakurai, Miwa Kubo, Megumi Nakai, Kosho Makino, Mitsuko Ogata, Hironobu Takahashi, Yoshiyasu Fukuyama.
Abstract
The syntheses of several neovibsanin derivatives were carried out in order to elucidate the simple structure required for displaying neurite outgrowth activity. In addition, a fluorescent probe molecule was synthesized and the analysis of its behavior in the PC12 cell line showed that the neovibsanins accumulate on the outer edge of the cell at the site of formation of prominences.Entities:
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Year: 2012 PMID： 22305582 DOI： 10.1016/j.bmcl.2012.01.006
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823