Literature DB >> 22302858

Saw-scaled viper bites in Sri Lanka: is it a different subspecies? Clinical evidence from an authenticated case series.

Ariaranee Gnanathasan1, Chaturaka Rodrigo, Thambipillai Peranantharajah, Anthonia Coonghe.   

Abstract

The saw-scaled viper (SSV) (Echis carinatus) is considered to be a highly venomous snake in Sri Lanka despite any published clinical justification. Being a rarity, the clinical profile of SSV bites is not well established in Sri Lanka. We report a series of 48 (n-48) SSV bites from the Northern Province of Sri Lanka. The majority (65%) of victims had evidence of local envenoming at the site of the bite; however, 29% showed spontaneous bleeding and 71% had coagulopathy. There were no deaths in the series. The envenoming was mild in contrast to the mortality and significant morbidity associated with SSV bites in West Africa and some parts of India. These observations need to be further explored with laboratory studies to identify the venom components, study of morphological characteristics, and genetic profiling of the Sri Lankan SSV to see if it is different from the subspecies found elsewhere.

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Year:  2012        PMID: 22302858      PMCID: PMC3269276          DOI: 10.4269/ajtmh.2012.11-0447

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  10 in total

1.  Snake bites in north east Sri Lanka.

Authors:  J S Whitehall
Journal:  Rural Remote Health       Date:  2007-12-12       Impact factor: 1.759

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Authors:  R N Bhat
Journal:  J Indian Med Assoc       Date:  1974-12-16

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4.  Poisoning by bites of the saw-scaled or carpet viper (Echis carinatus) in Nigeria.

Authors:  D A Warrell; B M Greenwood; L D Ormerod; H M Pope; B J Watkins; C R Prentice
Journal:  Q J Med       Date:  1977-01

5.  When continents collide: phylogeny, historical biogeography and systematics of the medically important viper genus Echis (Squamata: Serpentes: Viperidae).

Authors:  Catharine E Pook; Ulrich Joger; Nikolaus Stümpel; Wolfgang Wüster
Journal:  Mol Phylogenet Evol       Date:  2009-08-08       Impact factor: 4.286

6.  The importance of bites by the saw-scaled or carpet viper (Echis carinatus): epidemiological studies in Nigeria and a review of the world literature.

Authors:  D A Warrell; C Arnett
Journal:  Acta Trop       Date:  1976       Impact factor: 3.112

7.  Effects of snake venom proteases on human fibrinogen chains.

Authors:  Alessio Cortelazzo; Roberto Guerranti; Luca Bini; Nnadozie Hope-Onyekwere; Chiara Muzzi; Roberto Leoncini; Roberto Pagani
Journal:  Blood Transfus       Date:  2010-06       Impact factor: 3.443

8.  Local tissue destruction and procoagulation properties of Echis carinatus venom: inhibition by Vitis vinifera seed methanol extract.

Authors:  Y H Mahadeswaraswamy; S Nagaraju; K S Girish; K Kemparaju
Journal:  Phytother Res       Date:  2008-07       Impact factor: 5.878

9.  Rediscovery of severe saw-scaled viper (Echis sochureki) envenoming in the Thar desert region of Rajasthan, India.

Authors:  D K Kochar; P D Tanwar; Robert L Norris; M Sabir; K C Nayak; T D Agrawal; V P Purohit; A Kochar; Ian D Simpson
Journal:  Wilderness Environ Med       Date:  2007       Impact factor: 1.518

10.  Hemostatic abnormalities following Echis carinatus (saw-scaled viper) envenomation in the rhesus monkey.

Authors:  K S Chugh; D Mohanthy; Y Pal; K C Das; N K Ganguly; R N Chakravarty
Journal:  Am J Trop Med Hyg       Date:  1981-09       Impact factor: 2.345

  10 in total
  10 in total

Review 1.  Role of biomarkers of nephrotoxic acute kidney injury in deliberate poisoning and envenomation in less developed countries.

Authors:  Fahim Mohamed; Zoltan H Endre; Nicholas A Buckley
Journal:  Br J Clin Pharmacol       Date:  2015-05-28       Impact factor: 4.335

2.  Severe Viperidae envenomation complicated by a state of shock, acute kidney injury, and gangrene presenting late at the emergency department: a case report.

Authors:  Agnès Esiéné; Paul Owono Etoundi; Joel Noutakdie Tochie; Arlette Junette Mbengono Metogo; Jacqueline Ze Minkande
Journal:  BMC Emerg Med       Date:  2019-03-12

3.  Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram).

Authors:  Gotravalli V Rudresha; Amog P Urs; Vaddarahally N Manjuprasanna; Mallanayakanakatte D Milan Gowda; Krishnegowda Jayachandra; Rajesh Rajaiah; Bannikuppe S Vishwanath
Journal:  PLoS Negl Trop Dis       Date:  2021-02-02

4.  Saw-scaled viper envenoming complicated with acute myocardial infarction.

Authors:  Selladurai Pirasath; Dilani Gajan; Mahesan Guruparan; Arumugam Murugananthan; Ariaranee Gnanathasan
Journal:  SAGE Open Med Case Rep       Date:  2021-04-10

5.  Thrombotic microangiopathy following saw-scaled viper (Echis carinatus) envenoming in Sri Lanka.

Authors:  Selladurai Pirasath; Chandrakulasegeran Athirayan; Dilani Gajan
Journal:  SAGE Open Med Case Rep       Date:  2021-07-13

6.  Life threatening intracerebral haemorrhage following saw-scaled viper (Echis carinatus) envenoming--authenticated case report from Sri Lanka.

Authors:  Chathuranga Lakmal Fonseka; Vijayabala Jeevagan; Christeine Ariaranee Gnanathasan
Journal:  BMC Emerg Med       Date:  2013-04-08

7.  Blood coagulation induced by Iranian saw-scaled viper (echis carinatus) venom: identification, purification and characterization of a prothrombin activator.

Authors:  Mahdi Babaie; Hossein Salmanizadeh; Hossein Zolfagharian
Journal:  Iran J Basic Med Sci       Date:  2013-11       Impact factor: 2.699

8.  A study of snake bite among children presenting to a paediatric ward in the main Teaching Hospital of North Central province of Sri Lanka.

Authors:  Roshini Kilanthi Karunanayake; Dissanayake Mohottalage Randima Dissanayake; Aranjan Lionel Karunanayake
Journal:  BMC Res Notes       Date:  2014-07-29

9.  Proteomics and antivenomics of Echis carinatus carinatus venom: Correlation with pharmacological properties and pathophysiology of envenomation.

Authors:  Aparup Patra; Bhargab Kalita; Abhishek Chanda; Ashis K Mukherjee
Journal:  Sci Rep       Date:  2017-12-07       Impact factor: 4.379

10.  Assessment of quality and pre-clinical efficacy of a newly developed polyvalent antivenom against the medically important snakes of Sri Lanka.

Authors:  Aparup Patra; Bhargab Kalita; Milind V Khadilkar; Nitin C Salvi; Pravin V Shelke; Ashis K Mukherjee
Journal:  Sci Rep       Date:  2021-09-14       Impact factor: 4.379

  10 in total

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