Literature DB >> 22302584

Ligand binding assays in the 21st Century laboratory: automation.

Ago B Ahene1, Chris Morrow, David Rusnak, Susan Spitz, Joel Usansky, Holger Pils, Francesca Civoli, Kinnari Pandya, Brian Sue, Daniel Leach, John Derent.   

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Year:  2012        PMID： 22302584      PMCID： PMC3291192          DOI： 10.1208/s12248-012-9323-z

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


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  6 in total

1.  Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules.

Authors:  Binodh DeSilva; Wendell Smith; Russell Weiner; Marian Kelley; JoMarie Smolec; Ben Lee; Masood Khan; Richard Tacey; Howard Hill; Abbie Celniker
Journal:  Pharm Res       Date:  2003-11       Impact factor: 4.200

2.  Strategies to minimize variability and bias associated with manual pipetting in ligand binding assays to assure data quality of protein therapeutic quantification.

Authors:  Kinnari Pandya; Chad A Ray; Laura Brunner; Jin Wang; Jean W Lee; Binodh DeSilva
Journal:  J Pharm Biomed Anal       Date:  2010-04-28       Impact factor: 3.935

3.  Application of multi-factorial design of experiments to successfully optimize immunoassays for robust measurements of therapeutic proteins.

Authors:  Chad A Ray; Vimal Patel; Judy Shih; Chris Macaraeg; Yuling Wu; Theingi Thway; Mark Ma; Jean W Lee; Binodh Desilva
Journal:  J Pharm Biomed Anal       Date:  2008-12-06       Impact factor: 3.935

Review 4.  An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors.

Authors:  Angela Cacace; Martyn Banks; Timothy Spicer; Francesca Civoli; John Watson
Journal:  Drug Discov Today       Date:  2003-09-01       Impact factor: 7.851

5.  Optimizing ELISAs for precision and robustness using laboratory automation and statistical design of experiments.

Authors:  Daniel Joelsson; Phil Moravec; Matthew Troutman; Joseph Pigeon; Pete DePhillips
Journal:  J Immunol Methods       Date:  2008-06-12       Impact factor: 2.303

6.  Application of experimental design techniques to optimize a competitive ELISA.

Authors:  G S Sittampalam; W C Smith; T W Miyakawa; D R Smith; C McMorris
Journal:  J Immunol Methods       Date:  1996-04-19       Impact factor: 2.303
  6 in total
  1 in total

1.  Ligand binding assays in the 21st century laboratory-a call for change.

Authors:  Chad A Ray; Ago B Ahene
Journal:  AAPS J       Date:  2012-04-03       Impact factor: 4.009
  1 in total

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