BACKGROUND: To describe the rationale and study design of a follow-up epidemiological eye study among Singaporean Malay adults. DESIGN: Follow-up prospective population-based study. PARTICIPANTS: Participants of the Singapore Malay Eye Study (SiMES-1), which was conducted from August 2004 to June 2006. METHODS: This is a follow-up study of the 3280 participants who participated in the SiMES-1 and are residing in Singapore. All participants of this follow-up study will undergo various standardized validated questionnaires on socio-demographics, quality of life and impact of visual impairment. Participants will undergo assessment of blood pressure, anthropometry, presenting and best corrected visual acuity, subjective refraction, ocular biometry, slit lamp and dilated eye examination, Goldmann tonometry, optic disc imaging, digital lens and retinal photography. Retinal tomography, retinal optical coherence topography and fundus autofluorescence will also be performed. Gonioscopy and visual fields examination will be performed on selected individuals. MAIN OUTCOME MEASURES: Incidence, risk factors and impact of visual impairment and major eye diseases. RESULTS: A total of 3280 people who participated in the SiMES-1 will be contacted and invited to participate in this follow-up study. It is estimated that 12.8% of the participants will be deceased and there will be an 80% participation rate for the survivors of SiMES-1 (approximately 2288 participants). CONCLUSION: SiMES-2 will be one of the few follow-up epidemiological eye studies among Asians and will determine the cumulative 6-year incidence, progression, risk factors and impact of major eye diseases in Singaporean Malay adults.
BACKGROUND: To describe the rationale and study design of a follow-up epidemiological eye study among Singaporean Malay adults. DESIGN: Follow-up prospective population-based study. PARTICIPANTS: Participants of the Singapore Malay Eye Study (SiMES-1), which was conducted from August 2004 to June 2006. METHODS: This is a follow-up study of the 3280 participants who participated in the SiMES-1 and are residing in Singapore. All participants of this follow-up study will undergo various standardized validated questionnaires on socio-demographics, quality of life and impact of visual impairment. Participants will undergo assessment of blood pressure, anthropometry, presenting and best corrected visual acuity, subjective refraction, ocular biometry, slit lamp and dilated eye examination, Goldmann tonometry, optic disc imaging, digital lens and retinal photography. Retinal tomography, retinal optical coherence topography and fundus autofluorescence will also be performed. Gonioscopy and visual fields examination will be performed on selected individuals. MAIN OUTCOME MEASURES: Incidence, risk factors and impact of visual impairment and major eye diseases. RESULTS: A total of 3280 people who participated in the SiMES-1 will be contacted and invited to participate in this follow-up study. It is estimated that 12.8% of the participants will be deceased and there will be an 80% participation rate for the survivors of SiMES-1 (approximately 2288 participants). CONCLUSION: SiMES-2 will be one of the few follow-up epidemiological eye studies among Asians and will determine the cumulative 6-year incidence, progression, risk factors and impact of major eye diseases in Singaporean Malay adults.
Authors: Preeti Gupta; Eva K Fenwick; Ryan E K Man; Alfred T L Gan; Charumathi Sabanayagam; Debra Quek; Chaoxu Qian; Chui Ming Gemmy Cheung; Ching-Yu Cheng; Ecosse L Lamoureux Journal: Sci Rep Date: 2022-05-19 Impact factor: 4.996
Authors: Preeti Gupta; Elizabeth Sidhartha; Michael J A Girard; Jean Martial Mari; Tien-Yin Wong; Ching-Yu Cheng Journal: PLoS One Date: 2014-05-05 Impact factor: 3.240
Authors: Saima Hilal; Xu Xin; Seow Li Ang; Chuen Seng Tan; Narayanaswamy Venketasubramanian; Wiro J Niessen; Henri Vrooman; Tien Yin Wong; Christopher Chen; Mohammad Kamran Ikram Journal: Medicine (Baltimore) Date: 2015-06 Impact factor: 1.889
Authors: Evelyn Li Min Tai; Ling-Jun Li; Wan Hitam Wan-Hazabbah; Tien-Yin Wong; Ismail Shatriah Journal: PLoS One Date: 2017-01-20 Impact factor: 3.240