Literature DB >> 22294708

Personalized cardiovascular medicine and drug development: time for a new paradigm.

Joseph Loscalzo1.   

Abstract

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Year:  2012        PMID: 22294708      PMCID: PMC3273851          DOI: 10.1161/CIRCULATIONAHA.111.089243

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


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  11 in total

Review 1.  Primer on medical genomics. Part XIV: Introduction to systems biology--a new approach to understanding disease and treatment.

Authors:  Nicole M Morel; Joanne M Holland; Jan van der Greef; Edward W Marple; Clary Clish; Joseph Loscalzo; Stephen Naylor
Journal:  Mayo Clin Proc       Date:  2004-05       Impact factor: 7.616

2.  Drug target identification using side-effect similarity.

Authors:  Monica Campillos; Michael Kuhn; Anne-Claude Gavin; Lars Juhl Jensen; Peer Bork
Journal:  Science       Date:  2008-07-11       Impact factor: 47.728

Review 3.  A network view of disease and compound screening.

Authors:  Eric E Schadt; Stephen H Friend; David A Shaywitz
Journal:  Nat Rev Drug Discov       Date:  2009-04       Impact factor: 84.694

Review 4.  The productivity crisis in pharmaceutical R&D.

Authors:  Fabio Pammolli; Laura Magazzini; Massimo Riccaboni
Journal:  Nat Rev Drug Discov       Date:  2011-06       Impact factor: 84.694

Review 5.  How were new medicines discovered?

Authors:  David C Swinney; Jason Anthony
Journal:  Nat Rev Drug Discov       Date:  2011-06-24       Impact factor: 84.694

6.  Controllability of complex networks.

Authors:  Yang-Yu Liu; Jean-Jacques Slotine; Albert-László Barabási
Journal:  Nature       Date:  2011-05-12       Impact factor: 49.962

Review 7.  Network medicine: a network-based approach to human disease.

Authors:  Albert-László Barabási; Natali Gulbahce; Joseph Loscalzo
Journal:  Nat Rev Genet       Date:  2011-01       Impact factor: 53.242

8.  Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling.

Authors:  Nikhil Wagle; Caroline Emery; Michael F Berger; Matthew J Davis; Allison Sawyer; Panisa Pochanard; Sarah M Kehoe; Cory M Johannessen; Laura E Macconaill; William C Hahn; Matthew Meyerson; Levi A Garraway
Journal:  J Clin Oncol       Date:  2011-03-07       Impact factor: 44.544

9.  Drug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors.

Authors:  Li Xie; Jerry Li; Lei Xie; Philip E Bourne
Journal:  PLoS Comput Biol       Date:  2009-05-15       Impact factor: 4.475

10.  Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.

Authors:  Joseph Loscalzo; Isaac Kohane; Albert-Laszlo Barabasi
Journal:  Mol Syst Biol       Date:  2007-07-10       Impact factor: 11.429

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  18 in total

Review 1.  Biomarker science: on a theme of personalized medicine.

Authors:  Richard C Becker; Susan Smyth
Journal:  J Thromb Thrombolysis       Date:  2012-07       Impact factor: 2.300

2.  Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association.

Authors:  Caroline S Fox; Jennifer L Hall; Donna K Arnett; Euan A Ashley; Christian Delles; Mary B Engler; Mason W Freeman; Julie A Johnson; David E Lanfear; Stephen B Liggett; Aldons J Lusis; Joseph Loscalzo; Calum A MacRae; Kiran Musunuru; L Kristin Newby; Christopher J O'Donnell; Stephen S Rich; Andre Terzic
Journal:  Circulation       Date:  2015-04-16       Impact factor: 29.690

Review 3.  The emerging paradigm of network medicine in the study of human disease.

Authors:  Stephen Y Chan; Joseph Loscalzo
Journal:  Circ Res       Date:  2012-07-20       Impact factor: 17.367

4.  Clinical implications of chronic heart failure phenotypes defined by cluster analysis.

Authors:  Tariq Ahmad; Michael J Pencina; Phillip J Schulte; Emily O'Brien; David J Whellan; Ileana L Piña; Dalane W Kitzman; Kerry L Lee; Christopher M O'Connor; G Michael Felker
Journal:  J Am Coll Cardiol       Date:  2014-10-21       Impact factor: 24.094

Review 5.  Toward new biomarkers of cardiometabolic diseases.

Authors:  Lee D Roberts; Robert E Gerszten
Journal:  Cell Metab       Date:  2013-06-13       Impact factor: 27.287

Review 6.  Advances in the treatment of aortic valve disease: is it time for companion diagnostics?

Authors:  Robert B Hinton
Journal:  Curr Opin Pediatr       Date:  2014-10       Impact factor: 2.856

7.  Using systems biology approaches to understand cardiac inflammation and extracellular matrix remodeling in the setting of myocardial infarction.

Authors:  Omid Ghasemi; Yonggang Ma; Merry L Lindsey; Yu-Fang Jin
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2014 Jan-Feb

8.  Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes.

Authors:  Haloom Rafehi; Antony Kaspi; Mark Ziemann; Jun Okabe; Tom C Karagiannis; Assam El-Osta
Journal:  Epigenetics       Date:  2017       Impact factor: 4.528

Review 9.  Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine.

Authors:  Elliott Antman; Scott Weiss; Joseph Loscalzo
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2012-05-11

10.  The pulmonary hypertension academic research consortium.

Authors:  Stuart Rich
Journal:  Pulm Circ       Date:  2013-01       Impact factor: 3.017

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