Literature DB >> 22293769

Evaluation and management of osteochondral lesions of the knee.

Y Julia Kao1, Julianne Ho, Christina R Allen.   

Abstract

Osteochondral lesions of the knee is a common disorder in adolescents, although it may present in children and adults. Despite the fact that the disorder was discovered more than a century ago, no specific causes have been identified, although relationships with ischemia, irregular ossification of epiphyseal cartilage, genetic influences, trauma, and endocrine disorders have been postulated. Taking a thorough history and performing a thorough physical examination will facilitate diagnosis of this condition. Radiographic and magnetic resonance imaging are useful diagnostic tools that aid in the evaluation. A comprehensive knowledge of the relevant anatomy and clinical progression of osteochondral lesions allows for a better understanding of the classification systems and, ultimately management of this disorder. The size, location, and stability of the lesion, as well as the patient's age, are crucial in determining optimal treatment. The spectrum of injury ranges from small, stable lesions, which can be treated nonoperatively, to unstable or displaced lesions, which may require surgical management. Surgical options include drilling of subchondral bone, curettage and microfracture, refixation of detached lesions, autologous osteochondral autograft procedures (eg, mosaicplasty, osteochondral autograft transfer system), autologous chondrocyte implantation, and osteochondral allograft resurfacing. This article provides a basic approach to the evaluation and management of osteochondral lesions, as well as indications for surgery.

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Year:  2011        PMID: 22293769     DOI: 10.3810/psm.2011.11.1940

Source DB:  PubMed          Journal:  Phys Sportsmed        ISSN: 0091-3847            Impact factor:   2.241


  5 in total

1.  In Vitro and In Vivo Studies of Alar-Nasal Cartilage Using Autologous Micro-Grafts: The Use of the Rigenera® Protocol in the Treatment of an Osteochondral Lesion of the Nose.

Authors:  Gabriele Ceccarelli; Pietro Gentile; Marco Marcarelli; Martina Balli; Flavio Lorenzo Ronzoni; Laura Benedetti; Maria Gabriella Cusella De Angelis
Journal:  Pharmaceuticals (Basel)       Date:  2017-06-13

2.  Image-Guided Chondrocyte Harvesting for Autologous Chondrocyte Implantation: Initial Feasibility Study with Human Cadaver and Pilot Clinical Experience.

Authors:  Bashir Zikria; Nima Hafezi-Nejad; Ian Patten; Alex Johnson; Arya Haj-Mirzaian; John H Wilckens; James R Ficke; Shadpour Demehri
Journal:  JB JS Open Access       Date:  2019-05-29

3.  Posterior Approach for the Treatment of an Osteochondral Defect on the Posterior Lateral Femoral Condyle.

Authors:  Ariel N Rodriguez; Lindsay C Roethke; Daniel J Liechti; Robert F LaPrade
Journal:  Arthrosc Tech       Date:  2022-02-18

Review 4.  3D Bioprinting of Cartilage for Orthopedic Surgeons: Reading between the Lines.

Authors:  Claudia Di Bella; Amanda Fosang; Davide M Donati; Gordon G Wallace; Peter F M Choong
Journal:  Front Surg       Date:  2015-08-13

5.  Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation.

Authors:  Junyi Liao; Ning Hu; Nian Zhou; Liangbo Lin; Chen Zhao; Shixiong Yi; Tingxu Fan; Wei Bao; Xi Liang; Hong Chen; Wei Xu; Cheng Chen; Qiang Cheng; Yongming Zeng; Weike Si; Zhong Yang; Wei Huang
Journal:  PLoS One       Date:  2014-02-13       Impact factor: 3.240

  5 in total

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