Probably role of citicoline in stroke rehabilitation: review of the literature.

Stroke is a leading cause of mortality and the main cause of severe and long-term disability in adults. Following treatment during the acute phase, there is a need to continue the treatment of the patients in the rehabilitation phase, in order to improve the outcome and daily life activities. This is the role of rehabilitation programs. Rehabilitation is focused on increasing brain plasticity to recover some of the lost functions, based on different methodologies, including pharmaco-therapy. In this context, the role of citicoline in the rehabilitation of patients with stroke is reviewed.