| Literature DB >> 22275505 |
Abstract
Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.Entities:
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Year: 2012 PMID: 22275505 PMCID: PMC3294137 DOI: 10.1158/1078-0432.CCR-11-3198
Source DB: PubMed Journal: Clin Cancer Res ISSN: 1078-0432 Impact factor: 12.531