Literature DB >> 22275505

PET imaging of tumor growth: not as easy as it looks.

Anthony F Shields1.   

Abstract

Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.

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Year:  2012        PMID: 22275505      PMCID: PMC3294137          DOI: 10.1158/1078-0432.CCR-11-3198

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  11 in total

1.  Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients.

Authors:  Kong M Li; Laurent P Rivory; Stephen J Clarke
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2005-04-19       Impact factor: 3.205

2.  A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention.

Authors:  Anthony F Shields; David A Briston; Samatha Chandupatla; Kirk A Douglas; Jawana Lawhorn-Crews; Jerry M Collins; Thomas J Mangner; Lance K Heilbrun; Otto Muzik
Journal:  Eur J Nucl Med Mol Imaging       Date:  2005-07-01       Impact factor: 9.236

3.  Kinetic analysis of 3'-deoxy-3'-18F-fluorothymidine in patients with gliomas.

Authors:  Mark Muzi; Alexander M Spence; Finbarr O'Sullivan; David A Mankoff; Joanne M Wells; John R Grierson; Jeanne M Link; Kenneth A Krohn
Journal:  J Nucl Med       Date:  2006-10       Impact factor: 10.057

4.  The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3'-fluoro-3'-deoxythymidine in human B-lymphoblast cells.

Authors:  David A Plotnik; Lena J McLaughlin; Jenny Chan; Joshua N Redmayne-Titley; Jeffrey L Schwartz
Journal:  Nucl Med Biol       Date:  2011-06-22       Impact factor: 2.408

5.  Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging.

Authors:  Erik H J G Aarntzen; Mangala Srinivas; Johannes H W De Wilt; Joannes F M Jacobs; W Joost Lesterhuis; Albert D Windhorst; Esther G Troost; Johannes J Bonenkamp; Michelle M van Rossum; Willeke A M Blokx; Roel D Mus; Otto C Boerman; Cornelis J A Punt; Carl G Figdor; Wim J G Oyen; I Jolanda M de Vries
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-24       Impact factor: 11.205

6.  2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.

Authors:  Paula Wells; Eric Aboagye; Roger N Gunn; Safiye Osman; Alan V Boddy; Gordon A Taylor; Imran Rafi; Andrew N Hughes; A Hilary Calvert; Pat M Price; David R Newell
Journal:  J Natl Cancer Inst       Date:  2003-05-07       Impact factor: 13.506

7.  Imaging proliferation in vivo with [F-18]FLT and positron emission tomography.

Authors:  A F Shields; J R Grierson; B M Dohmen; H J Machulla; J C Stayanoff; J M Lawhorn-Crews; J E Obradovich; O Muzik; T J Mangner
Journal:  Nat Med       Date:  1998-11       Impact factor: 53.440

8.  Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG.

Authors:  Andreas K Buck; Gisela Halter; Holger Schirrmeister; Jörg Kotzerke; Imke Wurziger; Gerhard Glatting; Torsten Mattfeldt; Bernd Neumaier; Sven N Reske; Martin Hetzel
Journal:  J Nucl Med       Date:  2003-09       Impact factor: 10.057

9.  [18F]Fluorothymidine positron emission tomography before and 7 days after gefitinib treatment predicts response in patients with advanced adenocarcinoma of the lung.

Authors:  Hee-Jung Sohn; You-Jung Yang; Jin-Sook Ryu; Seung Jun Oh; Ki Chun Im; Dae Hyuk Moon; Dae Ho Lee; Cheolwon Suh; Jung-Shin Lee; Sang-We Kim
Journal:  Clin Cancer Res       Date:  2008-11-15       Impact factor: 12.531

10.  Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells.

Authors:  Janet S Rasey; John R Grierson; Linda W Wiens; Pamella D Kolb; Jeffrey L Schwartz
Journal:  J Nucl Med       Date:  2002-09       Impact factor: 10.057

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  10 in total

1.  ¹⁸F-FLT    and ¹⁸F-FDOPA PET kinetics in recurrent brain tumors.

Authors:  Mirwais Wardak; Christiaan Schiepers; Timothy F Cloughesy; Magnus Dahlbom; Michael E Phelps; Sung-Cheng Huang
Journal:  Eur J Nucl Med Mol Imaging       Date:  2014-03-07       Impact factor: 9.236

2.  STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging.

Authors:  Keke Liang; Evan R Abt; Thuc M Le; Arthur Cho; Amanda M Dann; Jing Cui; Luyi Li; Khalid Rashid; Amanda L Creech; Liu Wei; Razmik Ghukasyan; Ethan W Rosser; Nanping Wu; Giuseppe Carlucci; Johannes Czernin; Timothy R Donahue; Caius G Radu
Journal:  Proc Natl Acad Sci U S A       Date:  2021-09-07       Impact factor: 11.205

3.  Monitoring tumor response with radiolabeled nucleoside analogs in a hepatoma-bearing mouse model early after doxisome(®) treatment.

Authors:  Chun-Yi Wu; Lin-Shan Chou; Pei-Chia Chan; Chung-Hsien Ho; Ming-Hsien Lin; Chih-Chieh Shen; Ren-Shyan Liu; Wuu-Jyh Lin; Hsin-Ell Wang
Journal:  Mol Imaging Biol       Date:  2013-06       Impact factor: 3.488

Review 4.  Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents.

Authors:  Natalie J Serkova; S Gail Eckhardt
Journal:  Front Oncol       Date:  2016-07-15       Impact factor: 6.244

Review 5.  Preclinical Applications of 3'-Deoxy-3'-[18F]Fluorothymidine in Oncology - A Systematic Review.

Authors:  Sonja Schelhaas; Kathrin Heinzmann; Vikram R Bollineni; Gerbrand M Kramer; Yan Liu; John C Waterton; Eric O Aboagye; Anthony F Shields; Dmitry Soloviev; Andreas H Jacobs
Journal:  Theranostics       Date:  2017-01-01       Impact factor: 11.556

6.  Response Monitoring with [18F]FLT PET and Diffusion-Weighted MRI After Cytotoxic 5-FU Treatment in an Experimental Rat Model for Colorectal Liver Metastases.

Authors:  Sandra Heskamp; Linda Heijmen; Danny Gerrits; Janneke D M Molkenboer-Kuenen; Edwin G W Ter Voert; Kathrin Heinzmann; Davina J Honess; Donna-Michelle Smith; John R Griffiths; Sabrina Doblas; Ralph Sinkus; Peter Laverman; Wim J G Oyen; Arend Heerschap; Otto C Boerman
Journal:  Mol Imaging Biol       Date:  2017-08       Impact factor: 3.488

7.  18F-FLT PET/CT as a Prognostic Imaging Biomarker of Disease-Specific Survival in Patients with Primary Soft-Tissue Sarcoma.

Authors:  Joseph G Crompton; Wesley R Armstrong; Mark A Eckardt; Ameen Seyedroudbari; William D Tap; Sarah M Dry; Evan R Abt; Jeremie Calais; Ken Herrmann; Johannes Czernin; Fritz C Eilber; Matthias R Benz
Journal:  J Nucl Med       Date:  2021-09-30       Impact factor: 11.082

8.  Involvement of endoplasmic reticulum stress in capsaicin-induced apoptosis of human pancreatic cancer cells.

Authors:  Shengzhang Lin; Jianhong Zhang; Hui Chen; Kangjie Chen; Fuji Lai; Jiang Luo; Zhaohong Wang; Heqi Bu; Riyuan Zhang; Honghai Li; Hongfei Tong
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-28       Impact factor: 2.629

Review 9.  Glioma surveillance imaging: current strategies, shortcomings, challenges and outlook.

Authors:  Gehad Abdalla; Ahmed Hammam; Mustafa Anjari; Dr Felice D'Arco; Dr Sotirios Bisdas
Journal:  BJR Open       Date:  2020-06-23

10.  Application of [18F]FLT-PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers.

Authors:  Liza Botros; Samara M A Jansen; Ali Ashek; Onno A Spruijt; Jelco Tramper; Anton V Noordegraaf; Jurjan Aman; Hans Harms; Frances S de Man; Marc C Huisman; Lan Zhao; Harm J Bogaard
Journal:  Pulm Circ       Date:  2021-06-30       Impact factor: 3.017

  10 in total

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