OBJECTIVES: : To measure the incidence of disability in individuals aged 90 years and older and examine factors that may increase risk of disability. DESIGN AND SETTING: : The 90+ Study, a longitudinal study of aging, initiated in January 2003 with follow-up through May 2009. PARTICIPANTS: : A total of 216 nondisabled, prospectively followed participants who were aged 90 years or older at baseline. MEASUREMENTS: : The incidence of disability was measured as needing help on one or more activities of daily living and calculated using person years. Risk factors were examined by using a Cox proportional hazards analysis. RESULTS: : The overall incidence of disability was 16.4% per year (95% confidence interval: 13.3-20.0) and did not differ by gender. Disability incidence increased with age from 8.3% in the 90-94 age group to 25.7% in the 95 years and older age group. Several factors were associated with increased risk of disability, including history of congestive heart failure, depression, poor self-rated quality of life, and cognitive impairment. CONCLUSION: : Disability incidence is high and increases rapidly with age in the oldest-old, with rates essentially tripling between ages 90-94 years and 95+ years. Some factors associated with increased risk of disability in younger elderly continue to be risk factors in the oldest-old. Because of the tremendous social and financial impact of disability and the rapid growth of the oldest-old, the development of strategies to delay disability in the elderly should be a priority for healthcare research.
OBJECTIVES: : To measure the incidence of disability in individuals aged 90 years and older and examine factors that may increase risk of disability. DESIGN AND SETTING: : The 90+ Study, a longitudinal study of aging, initiated in January 2003 with follow-up through May 2009. PARTICIPANTS: : A total of 216 nondisabled, prospectively followed participants who were aged 90 years or older at baseline. MEASUREMENTS: : The incidence of disability was measured as needing help on one or more activities of daily living and calculated using person years. Risk factors were examined by using a Cox proportional hazards analysis. RESULTS: : The overall incidence of disability was 16.4% per year (95% confidence interval: 13.3-20.0) and did not differ by gender. Disability incidence increased with age from 8.3% in the 90-94 age group to 25.7% in the 95 years and older age group. Several factors were associated with increased risk of disability, including history of congestive heart failure, depression, poor self-rated quality of life, and cognitive impairment. CONCLUSION: : Disability incidence is high and increases rapidly with age in the oldest-old, with rates essentially tripling between ages 90-94 years and 95+ years. Some factors associated with increased risk of disability in younger elderly continue to be risk factors in the oldest-old. Because of the tremendous social and financial impact of disability and the rapid growth of the oldest-old, the development of strategies to delay disability in the elderly should be a priority for healthcare research.
Authors: Michelle C Odden; William Jen Hoe Koh; Alice M Arnold; Andreea M Rawlings; Bruce M Psaty; Anne B Newman Journal: Am J Epidemiol Date: 2019-02-01 Impact factor: 4.897
Authors: Mini E Jacob; Megan M Marron; Robert M Boudreau; Michelle C Odden; Alice M Arnold; Anne B Newman Journal: J Gerontol A Biol Sci Med Sci Date: 2018-01-16 Impact factor: 6.053
Authors: Sara Sabeti; Zeinah Al-Darsani; Bryce Anthony Mander; Maria M Corrada; Claudia H Kawas Journal: Aging Clin Exp Res Date: 2018-09-03 Impact factor: 3.636
Authors: Hamed Al-Sinawi; Mohammed Al-Alawi; Rehab Al-Lawati; Ahmed Al-Harrasi; Mohammed Al-Shafaee; Samir Al-Adawi Journal: Sultan Qaboos Univ Med J Date: 2012-04-09
Authors: Szofia S Bullain; Maria M Corrada; Barbara Agee Shah; Farah H Mozaffar; Martina Panzenboeck; Claudia H Kawas Journal: JAMA Neurol Date: 2013-01 Impact factor: 18.302
Authors: Adam J Santanasto; Megan M Marron; Robert M Boudreau; Mary F Feitosa; Mary K Wojczynski; Konstantin G Arbeev; Bharat Thyagarajan; Nicole Schupf; Eric Stallard; Paola Sebastiani; Stephanie Cosentino; Kaare Christensen; Anne B Newman Journal: J Gerontol A Biol Sci Med Sci Date: 2020-04-17 Impact factor: 6.053