Literature DB >> 2226800

Membrane lateral pressure as a modulator of glycerol-3-phosphate dehydrogenase activity.

E Amler1, R Jasińska, Z Drahota, J Zborowski.   

Abstract

Michaelis-Menten kinetics of glycerol-3-phosphate dehydrogenase activity in proteoliposomes from brown adipose tissue mitochondria with exogenously added phospholipids or cholesterol was measured. It was shown that changes in membrane lipid composition affected the membrane lateral pressure and therefore modulated the enzyme activity, namely Vmax value. Contrarily, changes in surface charge caused by minute amounts of phosphatidylserine or charged organic substances influenced only the apparent Km value. The role of bulk phospholipids in regulation of glycerol-3-phosphate dehydrogenase is discussed.

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Year:  1990        PMID： 2226800     DOI： 10.1016/0014-5793(90)80398-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  5 in total

1.  Theoretical evaluation of a possible nature of the outer membrane potential of mitochondria.

Authors:  Victor V Lemeshko
Journal:  Eur Biophys J       Date:  2006-10-05       Impact factor: 1.733

2.  Long-term adaptation of Bacillus subtilis 168 to extreme pH affects chemical and physical properties of the cellular membrane.

Authors:  Denisa Petrackova; Jaroslav Vecer; Jaroslava Svobodova; Petr Herman
Journal:  J Membr Biol       Date:  2010-02-05       Impact factor: 1.843

Review 3.  Membrane properties that shape the evolution of membrane enzymes.

Authors:  Charles R Sanders; James M Hutchison
Journal:  Curr Opin Struct Biol       Date:  2018-03-27       Impact factor: 6.809

4.  Inhibition of mitochondrial ATPase by dicarbopolyborate, a new enzyme inhibitor.

Authors:  Z Drahota; V Mares; H Rauchová; P Saf; M Kalous
Journal:  J Bioenerg Biomembr       Date:  1994-10       Impact factor: 2.945

5.  Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity.

Authors:  T I Omotayo; G S Akinyemi; P A Omololu; B O Ajayi; A A Akindahunsi; J B T Rocha; I J Kade
Journal:  Redox Biol       Date:  2014-12-24       Impact factor: 11.799
  5 in total

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