Literature DB >> 22267621

Steroids as adjuvant treatment of sore throat in acute bacterial pharyngitis.

Simon C Schams1, Ran D Goldman.   

Abstract

QUESTION: I see many children suffering from sore throat and acute pharyngitis. Some adult studies describe faster pain relief when sore throat is treated with steroids. Would a single dose of a steroid, as an anti-inflammatory agent, provide accelerated pain relief for sore throat in children? ANSWER: A single dose of oral dexamethasone (0.6 mg/kg, maximum 10 mg) leads to significantly (P < .05) faster onset of pain relief and shorter suffering, especially in children with severe or exudative group A β-hemolytic streptococcus-positive acute pharyngitis.

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Year:  2012        PMID: 22267621      PMCID: PMC3264011     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  16 in total

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Journal:  J Emerg Med       Date:  1994 Sep-Oct       Impact factor: 1.484

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Authors:  Eduardo G Marvez-Valls; Ashley Stuckey; Amy A Ernst
Journal:  Acad Emerg Med       Date:  2002-01       Impact factor: 3.451

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Authors:  Blake Bulloch; Amin Kabani; Milton Tenenbein
Journal:  Ann Emerg Med       Date:  2003-05       Impact factor: 5.721

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Authors:  T P van Staa; C Cooper; H G M Leufkens; N Bishop
Journal:  J Bone Miner Res       Date:  2003-05       Impact factor: 6.741

6.  Penicillin for acute sore throat in children: randomised, double blind trial.

Authors:  Sjoerd Zwart; Maroeska M Rovers; Ruut A de Melker; Arno W Hoes
Journal:  BMJ       Date:  2003-12-06

Review 7.  Steroids as adjuvant therapy for acute pharyngitis in ambulatory patients: a systematic review.

Authors:  Katrin Korb; Martin Scherer; Jean-François Chenot
Journal:  Ann Fam Med       Date:  2010 Jan-Feb       Impact factor: 5.166

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Journal:  Ann Emerg Med       Date:  1993-02       Impact factor: 5.721

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Authors:  E G Marvez-Valls; A A Ernst; J Gray; W D Johnson
Journal:  Acad Emerg Med       Date:  1998-06       Impact factor: 3.451

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Authors:  R B Vukmir
Journal:  J Emerg Med       Date:  1992 Sep-Oct       Impact factor: 1.484

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  4 in total

1.  Phytochemical-rich medicinal plant extracts suppress bacterial antigens-induced inflammation in human tonsil epithelial cells.

Authors:  Niluni M Wijesundara; Satvir Sekhon-Loodu; Hp Vasantha Rupasinghe
Journal:  PeerJ       Date:  2017-06-22       Impact factor: 2.984

2.  Resveratrol treatment inhibits acute pharyngitis in the mice model through inhibition of PGE2/COX-2 expression.

Authors:  Zhaoyan Yu; Wei Xu; Haibo Wang
Journal:  Saudi J Biol Sci       Date:  2017-05-09       Impact factor: 4.219

3.  Anti-inflammatory activity of Yanshu spraying agent in animal models.

Authors:  Jianqiao Zhang; Hongsheng Wang; Tian Wang; Yating Chong; Pengfei Yu; Chengwen Lu; Yunli Xue; Fenghua Fu; Leiming Zhang
Journal:  Exp Ther Med       Date:  2012-10-25       Impact factor: 2.447

Review 4.  Pharyngitis.

Authors:  Ruth Weber
Journal:  Prim Care       Date:  2013-11-21       Impact factor: 2.907

  4 in total

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