OBJECTIVE: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. METHOD: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7+/-0.57, age 29.1+/-1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9+/-0.58, age 31.6+/-3.87 years). RESULTS: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHI(NREM)) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHI(REM). Total testosterone level was positively correlated with AHI(NREM), and androstenedione was negatively correlated with AHI(NREM). CONCLUSION: PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.
OBJECTIVE: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. METHOD: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7+/-0.57, age 29.1+/-1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9+/-0.58, age 31.6+/-3.87 years). RESULTS: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHI(NREM)) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHI(REM). Total testosterone level was positively correlated with AHI(NREM), and androstenedione was negatively correlated with AHI(NREM). CONCLUSION:PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.
Authors: Renae C Fernandez; Vivienne M Moore; Emer M Van Ryswyk; Tamara J Varcoe; Raymond J Rodgers; Wendy A March; Lisa J Moran; Jodie C Avery; R Doug McEvoy; Michael J Davies Journal: Nat Sci Sleep Date: 2018-02-01
Authors: Hassan Kahal; Ioannis Kyrou; Olalekan A Uthman; Anna Brown; Samantha Johnson; Peter D H Wall; Andrew Metcalfe; David G Parr; Abd A Tahrani; Harpal S Randeva Journal: Sleep Breath Date: 2019-05-20 Impact factor: 2.816