Literature DB >> 22263842

Gold-catalyzed furan/yne cyclizations for the regiodefined assembly of multisubstituted protected 1-naphthols.

Chengyu Wang1, Yifeng Chen, Xin Xie, Jun Liu, Yuanhong Liu.   

Abstract

The gold(I)-catalyzed intramolecular cycloisomerization of furan/ynes bearing a silyloxy or allyloxy group has been developed, which provides a highly efficient access to protected 1-naphthol derivatives with enal or enone moiety. The method offers several advantages such as high stereoselectivities, mild reaction conditions, and easily accessible starting materials. In addition, the naphthyl products could be further transformed into the important benzocoumarins in a one-pot procedure.

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Year:  2012        PMID: 22263842     DOI: 10.1021/jo202541p

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthesis of novel isoquinolinone and 1,2-dihydroisoquinoline scaffolds via Ugi reaction and ring opening reaction of furans.

Authors:  Fei Ji; Wen-bin Yi; Mu Sun; Mei-fang Lv; Chun Cai
Journal:  Mol Divers       Date:  2013-03-20       Impact factor: 2.943

Review 2.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

3.  Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity.

Authors:  Ruth Dorel; Antonio M Echavarren
Journal:  Chem Rev       Date:  2015-04-06       Impact factor: 60.622

  3 in total

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