PURPOSE: As part of the Mini-Sentinel pilot program, under contract with the Food and Drug Administration, an effort has been made to evaluate the validity of algorithms useful for identifying health outcomes of interest, including suicide and suicide attempt. METHOD: Literature was reviewed to evaluate how well medical episodes associated with these events could be identified in administrative or claims data sets from the USA or Canada. RESULTS: Six studies were found to include sufficient detail to assess performance characteristics of an algorithm on the basis of International Classification of Diseases, Ninth Revision, E-codes (950-959) for intentional self-injury. Medical records and death registry information were used to validate classification. Sensitivity ranged from 13.8% to 65%, and positive predictive value range from 4.0% to 100%. Study comparisons are difficult to interpret, however, as the studies differed substantially in many important elements, including design, sample, setting, and methods. Although algorithm performance varied widely, two studies located in prepaid medical plans reported that comparisons of database codes to medical charts could achieve good agreement. CONCLUSIONS: Insufficient data exist to support specific recommendations regarding a preferred algorithm, and caution should be exercised in interpreting clinical and pharmacological epidemiological surveillance and research that rely on these codes as measures of suicide-related outcomes.
PURPOSE: As part of the Mini-Sentinel pilot program, under contract with the Food and Drug Administration, an effort has been made to evaluate the validity of algorithms useful for identifying health outcomes of interest, including suicide and suicide attempt. METHOD: Literature was reviewed to evaluate how well medical episodes associated with these events could be identified in administrative or claims data sets from the USA or Canada. RESULTS: Six studies were found to include sufficient detail to assess performance characteristics of an algorithm on the basis of International Classification of Diseases, Ninth Revision, E-codes (950-959) for intentional self-injury. Medical records and death registry information were used to validate classification. Sensitivity ranged from 13.8% to 65%, and positive predictive value range from 4.0% to 100%. Study comparisons are difficult to interpret, however, as the studies differed substantially in many important elements, including design, sample, setting, and methods. Although algorithm performance varied widely, two studies located in prepaid medical plans reported that comparisons of database codes to medical charts could achieve good agreement. CONCLUSIONS: Insufficient data exist to support specific recommendations regarding a preferred algorithm, and caution should be exercised in interpreting clinical and pharmacological epidemiological surveillance and research that rely on these codes as measures of suicide-related outcomes.
Authors: Sarah A Arias; Edwin D Boudreaux; Elizabeth Chen; Ivan Miller; Carlos A Camargo; Richard N Jones; Lisa Uebelacker Journal: Arch Suicide Res Date: 2019-06-11
Authors: Jason R Randall; Leslie L Roos; Lisa M Lix; Laurence Y Katz; James M Bolton Journal: Int J Methods Psychiatr Res Date: 2017-02-24 Impact factor: 4.035
Authors: Christine Y Lu; Christine Stewart; Ameena T Ahmed; Brian K Ahmedani; Karen Coleman; Laurel A Copeland; Enid M Hunkeler; Matthew D Lakoma; Jeanne M Madden; Robert B Penfold; Donna Rusinak; Fang Zhang; Stephen B Soumerai Journal: Pharmacoepidemiol Drug Saf Date: 2014-02 Impact factor: 2.890
Authors: Joshua J Gagne; Jennifer M Polinski; Wenlei Jiang; Sarah K Dutcher; Jing Xie; Joyce Lii; Lisa A Fulchino; Aaron S Kesselheim Journal: Drugs Date: 2017-03 Impact factor: 9.546
Authors: Sidra Goldman-Mellor; Kevin Kwan; Jonathan Boyajian; Paul Gruenewald; Paul Brown; Deborah Wiebe; Magdalena Cerdá Journal: Gen Hosp Psychiatry Date: 2018-12-08 Impact factor: 3.238
Authors: Greta A Bushnell; Bradley N Gaynes; Scott N Compton; Stacie B Dusetzina; M Alan Brookhart; Til Stürmer Journal: Depress Anxiety Date: 2018-10-24 Impact factor: 6.505
Authors: James A Naifeh; Robert J Ursano; Ronald C Kessler; Pablo A Aliaga; Holly B Herberman Mash; Carol S Fullerton; Tsz Hin Hinz Ng; Hieu M Dinh; Oscar I Gonzalez; Cara M Stokes; Gary H Wynn; Tzu-Cheg Kao; Nancy A Sampson; Murray B Stein Journal: Suicide Life Threat Behav Date: 2019-09-23