Literature DB >> 22261959

A new therapeutic strategy for malaria: targeting T cell exhaustion.

Gordon J Freeman, Arlene H Sharpe.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22261959      PMCID： PMC3690321          DOI： 10.1038/ni.2211

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


× No keyword cloud information.
  15 in total

1.  Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Authors:  Hyun-Tak Jin; Ana C Anderson; Wendy G Tan; Erin E West; Sang-Jun Ha; Koichi Araki; Gordon J Freeman; Vijay K Kuchroo; Rafi Ahmed
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-02       Impact factor: 11.205

2.  Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer.

Authors:  Junko Matsuzaki; Sacha Gnjatic; Paulette Mhawech-Fauceglia; Amy Beck; Austin Miller; Takemasa Tsuji; Cheryl Eppolito; Feng Qian; Shashikant Lele; Protul Shrikant; Lloyd J Old; Kunle Odunsi
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-12       Impact factor: 11.205

3.  Restoring function in exhausted CD8 T cells during chronic viral infection.

Authors:  Daniel L Barber; E John Wherry; David Masopust; Baogong Zhu; James P Allison; Arlene H Sharpe; Gordon J Freeman; Rafi Ahmed
Journal:  Nature       Date:  2005-12-28       Impact factor: 49.962

4.  Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates.

Authors:  Julie R Brahmer; Charles G Drake; Ira Wollner; John D Powderly; Joel Picus; William H Sharfman; Elizabeth Stankevich; Alice Pons; Theresa M Salay; Tracee L McMiller; Marta M Gilson; Changyu Wang; Mark Selby; Janis M Taube; Robert Anders; Lieping Chen; Alan J Korman; Drew M Pardoll; Israel Lowy; Suzanne L Topalian
Journal:  J Clin Oncol       Date:  2010-06-01       Impact factor: 44.544

5.  IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.

Authors:  David G Brooks; Sang-Jun Ha; Heidi Elsaesser; Arlene H Sharpe; Gordon J Freeman; Michael B A Oldstone
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-15       Impact factor: 11.205

6.  Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

Authors:  E John Wherry; Sang-Jun Ha; Susan M Kaech; W Nicholas Haining; Surojit Sarkar; Vandana Kalia; Shruti Subramaniam; Joseph N Blattman; Daniel L Barber; Rafi Ahmed
Journal:  Immunity       Date:  2007-10-18       Impact factor: 31.745

7.  Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients.

Authors:  Julien Fourcade; Zhaojun Sun; Mourad Benallaoua; Philippe Guillaume; Immanuel F Luescher; Cindy Sander; John M Kirkwood; Vijay Kuchroo; Hassane M Zarour
Journal:  J Exp Med       Date:  2010-09-06       Impact factor: 14.307

Review 8.  PD-1 and its ligands in tolerance and immunity.

Authors:  Mary E Keir; Manish J Butte; Gordon J Freeman; Arlene H Sharpe
Journal:  Annu Rev Immunol       Date:  2008       Impact factor: 28.527

Review 9.  Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.

Authors:  Gordon J Freeman; E John Wherry; Rafi Ahmed; Arlene H Sharpe
Journal:  J Exp Med       Date:  2006-09-25       Impact factor: 14.307

10.  Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

Authors:  Shawn D Blackburn; Haina Shin; W Nicholas Haining; Tao Zou; Creg J Workman; Antonio Polley; Michael R Betts; Gordon J Freeman; Dario A A Vignali; E John Wherry
Journal:  Nat Immunol       Date:  2008-11-30       Impact factor: 25.606
View more
  9 in total

1.  Cross-reactive immune responses as primary drivers of malaria chronicity.

Authors:  Eili Y Klein; Andrea L Graham; Manuel Llinás; Simon Levin
Journal:  Infect Immun       Date:  2013-10-14       Impact factor: 3.441

Review 2.  The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma.

Authors:  Kathleen M Mahoney; Gordon J Freeman; David F McDermott
Journal:  Clin Ther       Date:  2015-03-29       Impact factor: 3.393

3.  Parasites and immunotherapy: with or against?

Authors:  Hossein Yousofi Darani; Morteza Yousefi; Marzieh Safari; Rasool Jafari
Journal:  J Parasit Dis       Date:  2014-08-31

Review 4.  Combination cancer immunotherapy and new immunomodulatory targets.

Authors:  Kathleen M Mahoney; Paul D Rennert; Gordon J Freeman
Journal:  Nat Rev Drug Discov       Date:  2015-08       Impact factor: 84.694

5.  Ribonucleic acid (RNA) biosynthesis in human cancer.

Authors:  Omar S Hajjawi
Journal:  Cancer Cell Int       Date:  2015-02-21       Impact factor: 5.722

Review 6.  Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer.

Authors:  Matthew J Riese; Edmund K Moon; Bryon D Johnson; Steven M Albelda
Journal:  Front Cell Dev Biol       Date:  2016-10-17

7.  Summary and Recommendations from the National Cancer Institute's Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer.

Authors:  Seth P Lerner; Dean F Bajorin; Colin P Dinney; Jason A Efstathiou; Susan Groshen; Noah M Hahn; Donna Hansel; David Kwiatkowski; Michael O'Donnell; Jonathan Rosenberg; Robert Svatek; Jeffrey S Abrams; Hikmat Al-Ahmadie; Andrea B Apolo; Joaquim Bellmunt; Margaret Callahan; Eugene K Cha; Charles Drake; Jonathan Jarow; Ashish Kamat; William Kim; Margaret Knowles; Bhupinder Mann; Luigi Marchionni; David McConkey; Lisa McShane; Nilsa Ramirez; Andrew Sharabi; Arlene H Sharpe; David Solit; Catherine M Tangen; Abdul Tawab Amiri; Eliezer Van Allen; Pamela J West; J A Witjes; Diane Zipursky Quale
Journal:  Bladder Cancer       Date:  2016-04-27

Review 8.  Control of NK Cell Activation by Immune Checkpoint Molecules.

Authors:  Asma Beldi-Ferchiou; Sophie Caillat-Zucman
Journal:  Int J Mol Sci       Date:  2017-10-12       Impact factor: 5.923

9.  Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression.

Authors:  Ana Villegas-Mendez; Garima Khandelwal; Lucy M McGowan; Rebecca S Dookie; Michael J Haley; Charlotte George; David Sims; Graham M Lord; Linda V Sinclair; Richard G Jenner; Kevin N Couper
Journal:  J Immunol       Date:  2020-08-17       Impact factor: 5.422
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.