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Literature DB >> 22259562

(2E)-1-(5-Bromo-thio-phen-2-yl)-3-(2,3,4-trimeth-oxy-phen-yl)prop-2-en-1-one.

K Sunitha, H C Devarajegowda, Waleed Fadl Ali Al-Eryani, Y Rajendra Prasad, A Uma Mahesh Kumar.

Abstract

In the title compound, C(16)H(15)BrO(4)S, the thio-phene ring is not coplanar with the benzene ring; the dihedral angle between the two planes is 11.08 (12)°. The crystal structure is characterized by C-H⋯O inter-actions. Weak intra-molecular C-H⋯O hydrogen bonds also occur.

Entities: Chemical Disease Gene

Year: 2011 PMID： 22259562 PMCID： PMC3254417 DOI： 10.1107/S1600536811052202

Source DB: PubMed Journal: Acta Crystallogr Sect E Struct Rep Online ISSN： 1600-5368

9 in total

1. Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.

Authors: C Zubieta; X Z He; R A Dixon; J P Noel
Journal: Nat Struct Biol Date: 2001-03

2. In vitro antifungal evaluation and structure-activity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall.

Authors: S N López; M V Castelli; S A Zacchino; J N Domínguez; G Lobo; J Charris-Charris; J C Cortés; J C Ribas; C Devia; A M Rodríguez; R D Enriz
Journal: Bioorg Med Chem Date: 2001-08 Impact factor: 3.641

3. Structure-activity relationship studies on chalcone derivatives. the potent inhibition of chemical mediators release.

Authors: Horng-Huey Ko; Lo-Ti Tsao; Kun-Lung Yu; Cheng-Tsung Liu; Jih-Pyang Wang; Chun-Nan Lin
Journal: Bioorg Med Chem Date: 2003-01-02 Impact factor: 3.641

4. Structure-activity relationships of antileishmanial and antimalarial chalcones.

Authors: Mei Liu; Prapon Wilairat; Simon L Croft; Agnes Lay-Choo Tan; Mei-Lin Go
Journal: Bioorg Med Chem Date: 2003-07-03 Impact factor: 3.641

5. Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design.

Authors: Yunxiang Lu; Yong Wang; Weiliang Zhu
Journal: Phys Chem Chem Phys Date: 2010-03-25 Impact factor: 3.676

1 in total

1. The crystal structures of six (2E)-3-aryl-1-(5-halogeno-thio-phen-2-yl)prop-2-en-1-ones.

Authors: Vasant S Naik; Hemmige S Yathirajan; Jerry P Jasinski; Victoria A Smolenski; Christopher Glidewell
Journal: Acta Crystallogr E Crystallogr Commun Date: 2015-08-26

1 in total

(2E)-1-(5-Bromo-thio-phen-2-yl)-3-(2,3,4-trimeth-oxy-phen-yl)prop-2-en-1-one.

1. Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.

2. In vitro antifungal evaluation and structure-activity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall.

3. Structure-activity relationship studies on chalcone derivatives. the potent inhibition of chemical mediators release.

4. Structure-activity relationships of antileishmanial and antimalarial chalcones.

5. Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design.

6. A short history of SHELX.

7. Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A.

Review 8. All in the family: aldose reductase and closely related aldo-keto reductases.

9. 2'-Carb-oxy-meth-oxy-4,4'-bis-(3-methyl-but-2-en-yloxy)chalcone.

1. The crystal structures of six (2E)-3-aryl-1-(5-halogeno-thio-phen-2-yl)prop-2-en-1-ones.