Literature DB >> 22258610

The contribution of bone to whole-organism physiology.

Gérard Karsenty1, Mathieu Ferron.   

Abstract

The mouse genetic revolution has shown repeatedly that most organs have more functions than expected. This has led to the realization that, in addition to a molecular and cellular approach, there is a need for a whole-organism study of physiology. The skeleton is an example of how a whole-organism approach to physiology can broaden the functions of a given organ, reveal connections of this organ with others such as the brain, pancreas and gut, and shed new light on the pathogenesis of degenerative diseases affecting multiple organs.

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Year:  2012        PMID： 22258610      PMCID： PMC9047059          DOI： 10.1038/nature10763

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


  87 in total

Review 1.  The neuroendocrine basis of anorexia nervosa and its impact on bone metabolism.

Authors:  Madhusmita Misra; Anne Klibanski
Journal:  Neuroendocrinology       Date:  2011-01-13       Impact factor: 4.914

2.  Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts.

Authors:  I A Silver; R J Murrills; D J Etherington
Journal:  Exp Cell Res       Date:  1988-04       Impact factor: 3.905

3.  Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Authors:  Mathieu Ferron; Jianwen Wei; Tatsuya Yoshizawa; Andrea Del Fattore; Ronald A DePinho; Anna Teti; Patricia Ducy; Gerard Karsenty
Journal:  Cell       Date:  2010-07-23       Impact factor: 41.582

4.  Lower uncarboxylated osteocalcin concentrations in children with prediabetes is associated with beta-cell function.

Authors:  Norman K Pollock; Paul J Bernard; Barbara A Gower; Caren M Gundberg; Karl Wenger; Sudipta Misra; Reda W Bassali; Catherine L Davis
Journal:  J Clin Endocrinol Metab       Date:  2011-04-20       Impact factor: 5.958

5.  A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.

Authors:  J C Brüning; M D Michael; J N Winnay; T Hayashi; D Hörsch; D Accili; L J Goodyear; C R Kahn
Journal:  Mol Cell       Date:  1998-11       Impact factor: 17.970

Review 6.  Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa.

Authors:  W Kaye; K Gendall; M Strober
Journal:  Biol Psychiatry       Date:  1998-11-01       Impact factor: 13.382

7.  A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure.

Authors:  Vijay K Yadav; Franck Oury; Nina Suda; Zhong-Wu Liu; Xiao-Bing Gao; Cyrille Confavreux; Kristen C Klemenhagen; Kenji F Tanaka; Jay A Gingrich; X Edward Guo; Laurence H Tecott; J John Mann; Rene Hen; Tamas L Horvath; Gerard Karsenty
Journal:  Cell       Date:  2009-09-04       Impact factor: 41.582

8.  Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.

Authors:  Marie Björnholm; Heike Münzberg; Rebecca L Leshan; Eneida C Villanueva; Sarah H Bates; Gwendolyn W Louis; Justin C Jones; Ryoko Ishida-Takahashi; Christian Bjørbaek; Martin G Myers
Journal:  J Clin Invest       Date:  2007-04-05       Impact factor: 14.808

9.  Relation of serum serotonin levels to bone density and structural parameters in women.

Authors:  Ulrike I Mödder; Sara J Achenbach; Shreyasee Amin; B Lawrence Riggs; L Joseph Melton; Sundeep Khosla
Journal:  J Bone Miner Res       Date:  2010-02       Impact factor: 6.741

Review 10.  Leptin and the regulation of body weight in mammals.

Authors:  J M Friedman; J L Halaas
Journal:  Nature       Date:  1998-10-22       Impact factor: 49.962
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  166 in total

Review 1.  The past 10 years-new hormones, new functions, new endocrine organs.

Authors:  Roger Bouillon; Daniel J Drucker; Ele Ferrannini; Steven Grinspoon; Clifford J Rosen; Paul Zimmet
Journal:  Nat Rev Endocrinol       Date:  2015-09-01       Impact factor: 43.330

Review 2.  A four-season molecule: osteocalcin. Updates in its physiological roles.

Authors:  Giovanni Lombardi; Silvia Perego; Livio Luzi; Giuseppe Banfi
Journal:  Endocrine       Date:  2014-08-27       Impact factor: 3.633

Review 3.  Bone Remodeling and Energy Metabolism: New Perspectives.

Authors:  Francisco J A de Paula; Clifford J Rosen
Journal:  Bone Res       Date:  2013-03-29       Impact factor: 13.567

Review 4.  Bone metastasis and the metastatic niche.

Authors:  Guangwen Ren; Mark Esposito; Yibin Kang
Journal:  J Mol Med (Berl)       Date:  2015-08-15       Impact factor: 4.599

5.  Physiology of Mechanotransduction: How Do Muscle and Bone "Talk" to One Another?

Authors:  Janalee Isaacson; Marco Brotto
Journal:  Clin Rev Bone Miner Metab       Date:  2014-06

Review 6.  Clinical implications of bone marrow adiposity.

Authors:  A G Veldhuis-Vlug; C J Rosen
Journal:  J Intern Med       Date:  2018-01-15       Impact factor: 8.989

7.  In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice.

Authors:  Julie Lacombe; Gerard Karsenty; Mathieu Ferron
Journal:  Mol Metab       Date:  2013-08-15       Impact factor: 7.422

Review 8.  Semaphorin 3A: A new player in bone remodeling.

Authors:  Ren Xu
Journal:  Cell Adh Migr       Date:  2013-01-01       Impact factor: 3.405

Review 9.  Silicon micro- and nanofabrication for medicine.

Authors:  Daniel Fine; Alessandro Grattoni; Randy Goodall; Shyam S Bansal; Ciro Chiappini; Sharath Hosali; Anne L van de Ven; Srimeenkashi Srinivasan; Xuewu Liu; Biana Godin; Louis Brousseau; Iman K Yazdi; Joseph Fernandez-Moure; Ennio Tasciotti; Hung-Jen Wu; Ye Hu; Steve Klemm; Mauro Ferrari
Journal:  Adv Healthc Mater       Date:  2013-04-15       Impact factor: 9.933

10.  Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis.

Authors:  Chenshuang Li; Zhong Zheng; Pin Ha; Xiaoyan Chen; Wenlu Jiang; Shan Sun; Feng Chen; Greg Asatrian; Emily A Berthiaume; Jong Kil Kim; Eric C Chen; Shen Pang; Xinli Zhang; Kang Ting; Chia Soo
Journal:  J Bone Miner Res       Date:  2018-06-29       Impact factor: 6.741
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