Literature DB >> 22256586

[Use of sugammadex in a patient with amyotrophic lateral sclerosis].

Mayuko Wachi1, Kenji Uehara, Waso Fujinaka, Makoto Takatori, Keiichi Tada.   

Abstract

Amyotrophic lateral sclerosis (ALS) is a degenerative disease involving motor neurons. The anesthetic problem is increased susceptibility to non-depolarizing muscle relaxants and the feasibility of spinal and epidural anesthesia. An 86-year-old man with ALS underwent colostomy to the ileus. We chose general anesthesia with propofol, remifentanil, rocuronium and sugammadex. We administered 30 mg (0.52 mg . kg-1) of rocuronium only for induction. TOF-count was 2 at the end of operation. At spontaneous neuromuscular recovery to TOF-count 3, we administered sugammadex 2.1 mg . kg-1. The patient emerged from general anesthesia smoothly, and was extubated. Post-operative course was uneventful. Our anesthetic management of ALS patient using sugammadex was successful. Further evidence is required to establish appropriate use of sugammadex for ALS patients.

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Year:  2011        PMID: 22256586

Source DB:  PubMed          Journal:  Masui        ISSN: 0021-4892


  4 in total

1.  Robot-assisted total gastrectomy for gastric cancer in a patient with amyotrophic lateral sclerosis receiving long-term tracheostomy invasive ventilation.

Authors:  Masaaki Nishi; Ryosuke Miyamoto; Kasane Shima; Hirokazu Miki; Hideo Terasawa; Chie Takasu; Kozo Yoshikawa; Takuro Oyama; Katsuya Tanaka; Yuishin Izumi; Mitsuo Shimada
Journal:  Int Cancer Conf J       Date:  2021-07-12

Review 2.  Palliative Care Issues in Amyotrophic Lateral Sclerosis: An Evidenced-Based Review.

Authors:  Chafic Y Karam; Sabrina Paganoni; Nanette Joyce; Gregory T Carter; Richard Bedlack
Journal:  Am J Hosp Palliat Care       Date:  2014-09-08       Impact factor: 2.500

3.  Important modifications by sugammadex, a modified γ-cyclodextrin, of ion currents in differentiated NSC-34 neuronal cells.

Authors:  Hung-Te Hsu; Yi-Ching Lo; Yan-Ming Huang; Yu-Ting Tseng; Sheng-Nan Wu
Journal:  BMC Neurosci       Date:  2017-01-03       Impact factor: 3.288

4.  Use of sugammadex in a patient with amyotrophic lateral sclerosis.

Authors:  Ebru Kelsaka; Deniz Karakaya; Eyüp Cağatayn Zengin
Journal:  Med Princ Pract       Date:  2012-10-13       Impact factor: 1.927

  4 in total

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