Literature DB >> 22255660

Robot-driven spinal epidural stimulation compared with conventional stimulation in adult spinalized rats.

F H Hsieh1, S F Giszter.   

Abstract

Epidural stimulation to trigger locomotion is a promising treatment after spinal cord injury (SCI). Continuous stimulation during locomotion is the conventional method. To improve recovery, we tested an innovative robot-driven epidural stimulation method, combined with a trunk-based neurorobotic system. The system was tested in rat, and the results were compared with the results of the neurorobotic therapy combined with the conventional epidural stimulation method. The rats had better recovery after treatment with the robot-driven epidural stimulation than conventional stimulation in our neurorobotic rehabilitation system.

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Year:  2011        PMID： 22255660      PMCID： PMC3722870          DOI： 10.1109/IEMBS.2011.6091437

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN： 1557-170X


  13 in total

1.  Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist.

Authors:  M Antri; D Orsal; J-Y Barthe
Journal:  Eur J Neurosci       Date:  2002-08       Impact factor: 3.386

2.  Initiating extension of the lower limbs in subjects with complete spinal cord injury by epidural lumbar cord stimulation.

Authors:  B Jilge; K Minassian; F Rattay; M M Pinter; F Gerstenbrand; H Binder; M R Dimitrijevic
Journal:  Exp Brain Res       Date:  2003-10-25       Impact factor: 1.972

3.  Plasticity of spinal cord reflexes after a complete transection in adult rats: relationship to stepping ability.

Authors:  Igor Lavrov; Yury P Gerasimenko; Ronaldo M Ichiyama; Gregoire Courtine; Hui Zhong; Roland R Roy; V Reggie Edgerton
Journal:  J Neurophysiol       Date:  2006-07-05       Impact factor: 2.714

4.  Spinal cord reflexes induced by epidural spinal cord stimulation in normal awake rats.

Authors:  Yury P Gerasimenko; Igor A Lavrov; Gregoire Courtine; Ronaldo M Ichiyama; Christine J Dy; Hui Zhong; Roland R Roy; V Reggie Edgerton
Journal:  J Neurosci Methods       Date:  2006-06-09       Impact factor: 2.390

5.  Epidural stimulation induced modulation of spinal locomotor networks in adult spinal rats.

Authors:  Igor Lavrov; Christine J Dy; Andy J Fong; Yury Gerasimenko; Grégoire Courtine; Hui Zhong; Roland R Roy; V Reggie Edgerton
Journal:  J Neurosci       Date:  2008-06-04       Impact factor: 6.167

6.  Hindlimb stepping movements in complete spinal rats induced by epidural spinal cord stimulation.

Authors:  R M Ichiyama; Yu P Gerasimenko; H Zhong; R R Roy; V R Edgerton
Journal:  Neurosci Lett       Date:  2005-08-05       Impact factor: 3.046

7.  Facilitation of stepping with epidural stimulation in spinal rats: role of sensory input.

Authors:  Igor Lavrov; Grégoire Courtine; Christine J Dy; Rubia van den Brand; Andy J Fong; Yuri Gerasimenko; Hui Zhong; Roland R Roy; V Reggie Edgerton
Journal:  J Neurosci       Date:  2008-07-30       Impact factor: 6.167

Review 8.  Training locomotor networks.

Authors:  V Reggie Edgerton; Grégoire Courtine; Yury P Gerasimenko; Igor Lavrov; Ronaldo M Ichiyama; Andy J Fong; Lance L Cai; Chad K Otoshi; Niranjala J K Tillakaratne; Joel W Burdick; Roland R Roy
Journal:  Brain Res Rev       Date:  2007-09-16

9.  Robot application of elastic fields to the pelvis of the spinal transected rat: a tool for detailed assessment and rehabilitation.

Authors:  Ubong I Udoekwere; Arun Ramakrishnan; Lollise Mbi; Simon F Giszter
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2006

10.  Step training reinforces specific spinal locomotor circuitry in adult spinal rats.

Authors:  Ronaldo M Ichiyama; Grégoire Courtine; Yury P Gerasimenko; Grace J Yang; Rubia van den Brand; Igor A Lavrov; Hui Zhong; Roland R Roy; V Reggie Edgerton
Journal:  J Neurosci       Date:  2008-07-16       Impact factor: 6.167
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  8 in total

1.  Motor primitives are determined in early development and are then robustly conserved into adulthood.

Authors:  Qi Yang; David Logan; Simon F Giszter
Journal:  Proc Natl Acad Sci U S A       Date:  2019-05-28       Impact factor: 11.205

Review 2.  Enhancing neural activity to drive respiratory plasticity following cervical spinal cord injury.

Authors:  Kristiina M Hormigo; Lyandysha V Zholudeva; Victoria M Spruance; Vitaliy Marchenko; Marie-Pascale Cote; Stephane Vinit; Simon Giszter; Tatiana Bezdudnaya; Michael A Lane
Journal:  Exp Neurol       Date:  2016-08-28       Impact factor: 5.330

3.  Trunk robot rehabilitation training with active stepping reorganizes and enriches trunk motor cortex representations in spinal transected rats.

Authors:  Chintan S Oza; Simon F Giszter
Journal:  J Neurosci       Date:  2015-05-06       Impact factor: 6.167

4.  Inducing hindlimb locomotor recovery in adult rat after complete thoracic spinal cord section using repeated treadmill training with perineal stimulation only.

Authors:  Olivier Alluin; Hugo Delivet-Mongrain; Serge Rossignol
Journal:  J Neurophysiol       Date:  2015-07-22       Impact factor: 2.714

5.  A pelvic implant orthosis in rodents, for spinal cord injury rehabilitation, and for brain machine interface research: construction, surgical implantation and validation.

Authors:  Ubong Ime Udoekwere; Chintan S Oza; Simon F Giszter
Journal:  J Neurosci Methods       Date:  2013-11-19       Impact factor: 2.390

6.  Plasticity and alterations of trunk motor cortex following spinal cord injury and non-stepping robot and treadmill training.

Authors:  Chintan S Oza; Simon F Giszter
Journal:  Exp Neurol       Date:  2014-04-03       Impact factor: 5.330

7.  Teaching Adult Rats Spinalized as Neonates to Walk Using Trunk Robotic Rehabilitation: Elements of Success, Failure, and Dependence.

Authors:  Ubong I Udoekwere; Chintan S Oza; Simon F Giszter
Journal:  J Neurosci       Date:  2016-08-10       Impact factor: 6.167

Review 8.  Spinal primitives and intra-spinal micro-stimulation (ISMS) based prostheses: a neurobiological perspective on the "known unknowns" in ISMS and future prospects.

Authors:  Simon F Giszter
Journal:  Front Neurosci       Date:  2015-03-20       Impact factor: 4.677
  8 in total

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