AIM: The purpose of the present study was to investigate whether individuals with pervasive developmental disorders (PDD) show differential activation during an emotional activation task compared with age- and sex-matched controls, by measuring changes in the concentration of oxygenated (oxyHb) and deoxygenated (deoxyHb) hemoglobin, using near-infrared spectroscopy (NIRS). METHODS: Fourteen patients with PDD and 14 age- and sex-matched healthy controls participated in the study. The relative changes of concentrations of oxyHb and deoxyHb were measured on NIRS during an implicit processing task of fearful expression using Japanese standard faces. RESULTS: PDD patients had significantly reduced oxyHb changes in the prefrontal cortex (PFC) compared to healthy controls. CONCLUSION: PFC dysfunction may exist in PDD.
AIM: The purpose of the present study was to investigate whether individuals with pervasive developmental disorders (PDD) show differential activation during an emotional activation task compared with age- and sex-matched controls, by measuring changes in the concentration of oxygenated (oxyHb) and deoxygenated (deoxyHb) hemoglobin, using near-infrared spectroscopy (NIRS). METHODS: Fourteen patients with PDD and 14 age- and sex-matched healthy controls participated in the study. The relative changes of concentrations of oxyHb and deoxyHb were measured on NIRS during an implicit processing task of fearful expression using Japanese standard faces. RESULTS:PDDpatients had significantly reduced oxyHb changes in the prefrontal cortex (PFC) compared to healthy controls. CONCLUSION:PFC dysfunction may exist in PDD.
Authors: Matthew M P Westgarth; Christy A Hogan; David L Neumann; David H K Shum Journal: Soc Cogn Affect Neurosci Date: 2021-03-24 Impact factor: 3.436
Authors: James C McPartland; Matthew D Lerner; Anjana Bhat; Tessa Clarkson; Allison Jack; Sheida Koohsari; David Matuskey; Goldie A McQuaid; Wan-Chun Su; Dominic A Trevisan Journal: J Autism Dev Disord Date: 2021-05-27