Literature DB >> 22241929

Relative impact of maternal depression and associated risk factors on offspring psychopathology.

Edward D Barker1, William Copeland, Barbara Maughan, Sara R Jaffee, Rudolf Uher.   

Abstract

BACKGROUND: In general, mothers with depression experience more environmental and family risk factors, and lead riskier lifestyles, than mothers who are not depressed. AIMS: To test whether the exposure of a child to risk factors associated with mental health adds to the prediction of child psychopathology beyond exposure to maternal depression.
METHOD: In 7429 mother-offspring pairs participating in the Avon Longitudinal Study of Parents and Children in the UK, maternal depression was assessed when the children were aged 1.5 years; multiple risk factor exposures were examined between birth and 2 years of age; and DSM-IV-based externalising and internalising diagnoses were evaluated when the children were 7.5 years of age.
RESULTS: Children of clinically depressed mothers were exposed to more risk factors associated with maternal mental health. Maternal depression increased diagnoses of externalising and internalising disorders, but a substantial portion of these associations was explained by increased risk factor exposure (41% for externalising and 37% for internalising disorders). At the same time, these risk exposures significantly increased the odds of both externalising and internalising diagnoses, over and above the influence of maternal depression.
CONCLUSIONS: Children of clinically depressed mothers are exposed to both maternal psychopathology and risks that are associated with maternal mental health. These results may explain why treating mothers with depression shows beneficial effects for children, but does not completely neutralise the increased risk of psychopathology and impairment.

Entities:  

Mesh:

Year:  2012        PMID: 22241929      PMCID: PMC3567912          DOI: 10.1192/bjp.bp.111.092346

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  32 in total

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4.  Cumulative socioeconomic status risk and observations of parent depression: Are there associations with child outcomes?

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7.  Preschoolers' Psychopathology and Temperament Predict Mothers' Later Mood Disorders.

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10.  Associations between adolescent depression and parental mental health, before and after treatment of adolescent depression.

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