| Literature DB >> 22239869 |
Erika L Finanger1, Barry Russman, Sean C Forbes, William D Rooney, Glenn A Walter, Krista Vandenborne.
Abstract
Studies have shown promise in using various approaches of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy to evaluate skeletal muscle involvement in Duchenne muscular dystrophy. However, these studies have mainly been performed using a cross-sectional design, and the correlation of these MRI changes with disease progression and disease severity has not been fully elucidated. Overall, skeletal muscle MRI is a powerful and sensitive technique in the evaluation of muscle disease, and its use as a biomarker for disease progression or therapeutic response in clinical trials deserves further study.Entities:
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Year: 2011 PMID: 22239869 PMCID: PMC3561672 DOI: 10.1016/j.pmr.2011.11.004
Source DB: PubMed Journal: Phys Med Rehabil Clin N Am ISSN: 1047-9651 Impact factor: 1.784