Literature DB >> 22239552

Anti-cellular and immunomodulatory potential of aqueous extract of Rhodiola imbricata rhizome.

K P Mishra1, Lilly Ganju, S B Singh.   

Abstract

In the present study, we have evaluated the anti-cellular and immunomodulatory potential of aqueous extract of Rhodiola imbricata rhizome (RAE). Rhodiola extract inhibited the proliferation of human T cell lymphoma cell line EL-4 and erythroleukemic cell line HL-60. Furthermore, treatment of human peripheral blood mononuclear cells (hPBMCs) with lipopolysaccharide (LPS) and RAE suppressed regulated upon activation, normal T cell expressed and secreted (RANTES) production. However, number of TNF-α spots was increased in RAE treated hPBMCs. The reverse transcriptase polymerase chain reaction (RT-PCR) analysis of RAE treated rat splenocytes confirmed the up regulation of TLR-4 mRNA expression. Therefore, the present study concludes that RAE has potent immune boosting activity which might be useful in immunocompromised individuals.

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Year:  2012        PMID： 22239552     DOI： 10.3109/08923973.2011.638307

Source DB:  PubMed          Journal:  Immunopharmacol Immunotoxicol        ISSN： 0892-3973            Impact factor:   2.730


  8 in total

1.  Modulatory effects of feeding pregnant and lactating mice Rhodiola kirilowii extracts on the immune system of offspring.

Authors:  Sławomir Lewicki; Barbara Joanna Bałan; Ewa Skopińska-Różewska; Robert Zdanowski; Marta Stelmasiak; Łukasz Szymański; Wanda Stankiewicz
Journal:  Exp Ther Med       Date:  2016-09-30       Impact factor: 2.447

2.  Effects of Rhodiola on production, health and gut development of broilers reared at high altitude in Tibet.

Authors:  Long Li; Honghui Wang; Xin Zhao
Journal:  Sci Rep       Date:  2014-11-24       Impact factor: 4.379

3.  The effect of feeding mice during gestation and nursing with Rhodiola kirilowii extracts or epigallocatechin on CD4 and CD8 cells number and distribution in the spleen of their progeny.

Authors:  Sławomir Lewicki; Piotr Orłowski; Małgorzata Krzyżowska; Anna Kiepura; Ewa Skopińska-Różewska; Robert Zdanowski
Journal:  Cent Eur J Immunol       Date:  2017-05-08       Impact factor: 2.085

4.  Supplementation of Plants with Immunomodulatory Properties during Pregnancy and Lactation-Maternal and Offspring Health Effects.

Authors:  Aneta Lewicka; Łukasz Szymański; Kamila Rusiecka; Anna Kucza; Anna Jakubczyk; Robert Zdanowski; Sławomir Lewicki
Journal:  Nutrients       Date:  2019-08-20       Impact factor: 5.717

5.  Chemometric profile of root extracts of Rhodiola imbricata Edgew. with hyphenated gas chromatography mass spectrometric technique.

Authors:  Amol B Tayade; Priyanka Dhar; Jatinder Kumar; Manu Sharma; Rajinder S Chauhan; Om P Chaurasia; Ravi B Srivastava
Journal:  PLoS One       Date:  2013-01-10       Impact factor: 3.240

6.  Administration of Rhodiola kirilowii Extracts during Mouse Pregnancy and Lactation Stimulates Innate but Not Adaptive Immunity of the Offspring.

Authors:  Sławomir Lewicki; Ewa Skopińska-Różewska; Aleksandra Brewczyńska; Robert Zdanowski
Journal:  J Immunol Res       Date:  2017-10-30       Impact factor: 4.818

Review 7.  Wound Healing and the Use of Medicinal Plants.

Authors:  Aleksandra Shedoeva; David Leavesley; Zee Upton; Chen Fan
Journal:  Evid Based Complement Alternat Med       Date:  2019-09-22       Impact factor: 2.629

Review 8.  Rhodiola plants: Chemistry and biological activity.

Authors:  Hsiu-Mei Chiang; Hsin-Chun Chen; Chin-Sheng Wu; Po-Yuan Wu; Kuo-Ching Wen
Journal:  J Food Drug Anal       Date:  2015-05-29       Impact factor: 6.157
  8 in total

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