Literature DB >> 22238756

Expression of circadian Per1 and Per2 genes in the liver and breast tumor tissues of HER2/neu transgenic mice of different age.

S N Kolomeichuk1, E V Gurov, T S Piskunova, M L Tyndyk, V N Anisimov.   

Abstract

The expression of Per1, Per2, and Cry1 circadian genes in the liver and breast tumors were studied by real-time PCR in FVB/N mice of different age transfected with HER-2/neu gene. The expression of Per1 and Per2 genes in breast tumor tissue decreased in comparison with their expression in the lever. The expression of these genes decreased with age in both the liver and tumor tissue.

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Year:  2011        PMID: 22238756     DOI: 10.1007/s10517-011-1295-y

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  3 in total

1.  Construction of a plasmid for overexpression of human circadian gene period2 and its biological activity in osteosarcoma cells.

Authors:  An-yuan Cheng; Yan Zhang; Hong-jun Mei; Shuo Fang; Peng Ji; Jian Yang; Ling Yu; Wei-chun Guo
Journal:  Tumour Biol       Date:  2015-01-07

2.  The Circadian Gene Per1 Plays an Important Role in Radiation-Induced Apoptosis and DNA Damage in Glioma.

Authors:  Ling Zhu; Qunli Wang; Yi Hu; Fan Wang
Journal:  Asian Pac J Cancer Prev       Date:  2019-07-01

3.  Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway.

Authors:  Niu Zhanfeng; Wang Chengquan; Xia Hechun; Wang Jun; Zhang Lijian; Ma Dede; Liu Wenbin; Yin Lei
Journal:  Oncotarget       Date:  2016-05-10
  3 in total

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