Literature DB >> 22238485

In vitro antiplasmodial properties of Flacourtia flavescens Willd. (Flacourtiaceae) and Rytigynia canthioides (Benth.) Robyns (Rubiaceae).

Micheline Agassounon Djikpo-Tchibozo1, Simplice D Karou, Souleymane Sanon, Fatiou Toukourou, Comlan de Souza.   

Abstract

The present study was conducted to investigate the in vitro antimalarial activity of Flacourtia flavescens Willd. (Flacourtiaceae) and Rytigynia canthioides (Benth.) Robyns (Rubiaceae). These two plants are used in Benin folk medicine to treat malaria and fever. Antimalarial activity was assayed on fresh clinical isolates of chloroquine resistant Plasmodium falciparum using the in vitro semi-microtest. The results revealed that the IC(50) varied from 1.55 to 22.36µg/ml. F. flavescens hydro methanol extract was more active than R. canthioides. The study demonstrated scientific rationale behind the traditional usage of these plants, however further bioactivity guided phytochemical analyses are necessary to identify the active principles.

Entities:  

Keywords:  Flacourtia flavescens; Plasmodium falciparum; Rytigynia canthioides; antiplasmodial

Mesh：

Substances：

Year:  2010        PMID： 22238485      PMCID： PMC3218440     

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN： 2505-0044


  10 in total

1.  Studies on medicinal plants of Ivory Coast: investigation of Sida acuta for in vitro antiplasmodial activities and identification of an active constituent.

Authors:  J T Banzouzi; R Prado; H Menan; A Valentin; C Roumestan; M Mallié; Y Pelissier; Y Blache
Journal:  Phytomedicine       Date:  2004       Impact factor: 5.340

2.  In vitro antiplasmodial and antibacterial activities of Canthium multiflorum Schum and Thonn (Rubiacea) extracts.

Authors:  E F O Akomo; C Zongo; S D Karou; L C Obame; A Savadogo; C Atteke; A S Traore
Journal:  Pak J Biol Sci       Date:  2009-06-15

3.  Antiplasmodial activity of alkaloid extracts from Pavetta crassipes (K. Schum) and Acanthospermum hispidum (DC), two plants used in traditional medicine in Burkina Faso.

Authors:  S Sanon; N Azas; M Gasquet; E Ollivier; V Mahiou; N Barro; N Cuzin-Ouattara; A S Traore; F Esposito; G Balansard; P Timon-David
Journal:  Parasitol Res       Date:  2003-04-04       Impact factor: 2.289

Review 4.  In vitro activities of strychnos alkaloids and extracts against Plasmodium falciparum.

Authors:  M Frederich; M P Hayette; M Tits; P De Mol; L Angenot
Journal:  Antimicrob Agents Chemother       Date:  1999-09       Impact factor: 5.191

5.  Ethnobotanical survey and in vitro antiplasmodial activity of plants used in traditional medicine in Burkina Faso.

Authors:  S Sanon; E Ollivier; N Azas; V Mahiou; M Gasquet; C T Ouattara; I Nebie; A S Traore; F Esposito; G Balansard; P Timon-David; F Fumoux
Journal:  J Ethnopharmacol       Date:  2003-06       Impact factor: 4.360

Review 6.  Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity?

Authors:  J Rubén Gómez Castellanos; José M Prieto; Michael Heinrich
Journal:  J Ethnopharmacol       Date:  2008-11-01       Impact factor: 4.360

7.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

8.  In vitro study of drug sensitivity of Plasmodium falciparum: evaluation of a new semi-micro test.

Authors:  J Le Bras; P Deloron
Journal:  Am J Trop Med Hyg       Date:  1983-05       Impact factor: 2.345

9.  In vitro and in vivo chloroquine-potentiating action of Strychnos myrtoides alkaloids against chloroquine-resistant strains of Plasmodium malaria.

Authors:  P Rasoanaivo; S Ratsimamanga-Urverg; R Milijaona; H Rafatro; A Rakoto-Ratsimamanga; C Galeffi; M Nicoletti
Journal:  Planta Med       Date:  1994-02       Impact factor: 3.352

10.  Antimalarial activity of Sida acuta Burm. f. (Malvaceae) and Pterocarpus erinaceus Poir. (Fabaceae).

Authors:  Damintoti Karou; Mamoudou H Dicko; Souleymane Sanon; Jacques Simpore; Alfred S Traore
Journal:  J Ethnopharmacol       Date:  2003-12       Impact factor: 4.360
  10 in total
  1 in total

1.  In Vivo Antiplasmodial Activity of Entandrophragma cylindricum (Sprague) Sprague Ethyl Acetate Extract in Plasmodium berghei-Infected Mice.

Authors:  Noumedem Anangmo Christelle Nadia; Yamssi Cédric; Ngongang Ouankou Christian; Simeni Njonnou Sylvain Raoul; Yondo Jeanette; Mounvera Abdel Azizi; Sop Foka Eric Igor; Djape Guangue Diane; Chahdini Gbambie Abass; Tsila Henri Gabriel; Mpoame Mbida
Journal:  J Parasitol Res       Date:  2020-11-13
  1 in total

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