BACKGROUND: Workplace exposures that can potentially cause both allergic occupational contact dermatitis (AOCD) and occupational asthma (OA) are not clearly identified. METHODS: Occupational contact allergens (OCAs) were identified using North American Contact Dermatitis Group (NACDG) data. Reference documents and systematic reviews were used to determine whether each OCA had been reported to potentially cause OA. The presence or absence of a sensitizer notation in occupational hygiene reference documents was also examined. RESULTS: The 10 most common OCAs were: epoxy resin*, thiuram, carba mix, nickel sulfate*, cobalt chloride*, potassium dichromate*, glyceryl thioglycolate, p-phenylenediamine*, formaldehyde* and glutaraldehyde*. Seven (indicated by *) were determined to be possible causes of OA. Information on sensitizing potential from OH reference materials contained conflicting information. CONCLUSIONS: Several common OCAs can also potentially cause OA. Inhalation and dermal exposures to these agents should be controlled and both OA and AOCD should be considered as possible health outcomes. Increased consistency in sensitizer notations is needed.
BACKGROUND: Workplace exposures that can potentially cause both allergic occupational contact dermatitis (AOCD) and occupational asthma (OA) are not clearly identified. METHODS:Occupational contact allergens (OCAs) were identified using North American Contact Dermatitis Group (NACDG) data. Reference documents and systematic reviews were used to determine whether each OCA had been reported to potentially cause OA. The presence or absence of a sensitizer notation in occupational hygiene reference documents was also examined. RESULTS: The 10 most common OCAs were: epoxy resin*, thiuram, carba mix, nickel sulfate*, cobalt chloride*, potassium dichromate*, glyceryl thioglycolate, p-phenylenediamine*, formaldehyde* and glutaraldehyde*. Seven (indicated by *) were determined to be possible causes of OA. Information on sensitizing potential from OH reference materials contained conflicting information. CONCLUSIONS: Several common OCAs can also potentially cause OA. Inhalation and dermal exposures to these agents should be controlled and both OA and AOCD should be considered as possible health outcomes. Increased consistency in sensitizer notations is needed.
Authors: Orianne Dumas; Raphäelle Varraso; Krislyn M Boggs; Alexis Descatha; Paul K Henneberger; Catherine Quinot; Frank E Speizer; Jan-Paul Zock; Nicole Le Moual; Carlos A Camargo Journal: Occup Environ Med Date: 2018-02-23 Impact factor: 4.402
Authors: Hung Chang Tsui; Steven Ronsmans; Laurens J De Sadeleer; Peter H M Hoet; Benoit Nemery; Jeroen A J Vanoirbeek Journal: Allergy Asthma Immunol Res Date: 2020-07 Impact factor: 5.764
Authors: Sharara Shakik; Victoria Arrandale; Dorothy Linn Holness; Jill S MacLeod; Christopher B McLeod; Alice Peter; Paul A Demers Journal: Occup Environ Med Date: 2019-07-18 Impact factor: 4.402