| Literature DB >> 22227738 |
Elliot Campbell1, Matthew Meredith, Shelley D Minteer, Scott Banta.
Abstract
The performance of immobilized enzyme systems is often limited by cofactor diffusion and regeneration. Here, we demonstrate an engineered enzyme capable of utilizing the minimal cofactor nicotinamide mononucleotide (NMN(+)) to address these limitations. Significant gains in performance are observed with NMN(+) in immobilized systems, despite a decreased turnover rate with the minimal cofactor. This journal is © The Royal Society of Chemistry 2012Entities:
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Year: 2012 PMID: 22227738 DOI: 10.1039/c2cc16156g
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222