PURPOSE: The primary objective of this clinical trial of patients on mechanical ventilation was to determine if a weaning protocol implemented solely by nurses could reduce the weaning time relative to usual care (UC). MATERIALS AND METHODS: This study is a prospective, randomized, controlled trial conducted from January 2007 to January 2009 that compared protocol-based weaning (PBW) with UC. A total of 122 patients who received invasive ventilation in the medical ICU of the Asan Medical Center were examined. Nurses operated the mechanical ventilators according to a predesigned ventilator-weaning protocol for the PBW group (n = 61), and intensive care unit (ICU) physicians managed weaning in the UC group (n = 61). RESULTS: There were no significant differences in the 2 groups at baseline. The number of patients who successfully discontinued mechanical ventilation was similar in the 2 groups (PBW, 46 patients, 75.4%; UC, 47 patients, 77.0%; P = .832). The weaning time was 47 hours (interquartile range, 24-168 hours) in the UC group and 25 hours (interquartile range, 5.75-134 hours) in the PBW group (P = .010). CONCLUSIONS: The weaning protocol administered by the nurses was safe and reduced the weaning time from mechanical ventilation in patients who were recovering from respiratory failure.
RCT Entities:
PURPOSE: The primary objective of this clinical trial of patients on mechanical ventilation was to determine if a weaning protocol implemented solely by nurses could reduce the weaning time relative to usual care (UC). MATERIALS AND METHODS: This study is a prospective, randomized, controlled trial conducted from January 2007 to January 2009 that compared protocol-based weaning (PBW) with UC. A total of 122 patients who received invasive ventilation in the medical ICU of the Asan Medical Center were examined. Nurses operated the mechanical ventilators according to a predesigned ventilator-weaning protocol for the PBW group (n = 61), and intensive care unit (ICU) physicians managed weaning in the UC group (n = 61). RESULTS: There were no significant differences in the 2 groups at baseline. The number of patients who successfully discontinued mechanical ventilation was similar in the 2 groups (PBW, 46 patients, 75.4%; UC, 47 patients, 77.0%; P = .832). The weaning time was 47 hours (interquartile range, 24-168 hours) in the UC group and 25 hours (interquartile range, 5.75-134 hours) in the PBW group (P = .010). CONCLUSIONS: The weaning protocol administered by the nurses was safe and reduced the weaning time from mechanical ventilation in patients who were recovering from respiratory failure.
Authors: Amir Vahedian-Azimi; Farshid Rahimi Bashar; Mohammad A Jafarabadi; Jennifer Stahl; Andrew C Miller Journal: Int J Crit Illn Inj Sci Date: 2020-12-29
Authors: Amir Vahedian-Azimi; Keivan Gohari-Moghadam; Farshid Rahimi-Bashar; Abbas Samim; Masoum Khoshfetrat; Seyyede Momeneh Mohammadi; Leonardo Cordeiro de Souza; Ata Mahmoodpoor Journal: Front Med (Lausanne) Date: 2022-07-22
Authors: Miriam Sánchez-Maciá; Jaime Miralles-Sancho; María José Castaño-Picó; Ana Pérez-Carbonell; Loreto Maciá-Soler Journal: Rev Lat Am Enfermagem Date: 2019-12-05