| Literature DB >> 22222943 |
David J Wild1, Ying Ding, Amit P Sheth, Lee Harland, Eric M Gifford, Michael S Lajiness.
Abstract
Systems chemical biology, the integration of chemistry, biology and computation to generate understanding about the way small molecules affect biological systems as a whole, as well as related fields such as chemogenomics, are central to emerging new paradigms of drug discovery such as drug repurposing and personalized medicine. Recent Semantic Web technologies such as RDF and SPARQL are technical enablers of systems chemical biology, facilitating the deployment of advanced algorithms for searching and mining large integrated datasets. In this paper, we aim to demonstrate how these technologies together can change the way that drug discovery is accomplished.Mesh：
Year: 2011 PMID： 22222943 DOI： 10.1016/j.drudis.2011.12.019
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851