Literature DB >> 22221792

Structural analysis of capsular polysaccharides expressed by Burkholderia mallei and Burkholderia pseudomallei.

Christian Heiss1, Mary N Burtnick, Zhirui Wang, Parastoo Azadi, Paul J Brett.   

Abstract

Capsular polysaccharides (CPSs) were isolated from O-polysaccharide deficient strains of Burkholderia mallei and Burkholderia pseudomallei using a modified hot phenol/water extraction procedure. Glycosyl composition, methylation, MALDI-TOF MS analyses as well as (1)H NMR spectroscopy including COSY, TOCSY, NOESY, HMBC and HSQC experiments identified the presence of two distinct CPS antigens in the samples exhibiting the following structures: This study confirms the ability of B. mallei to express a 6-deoxy-heptan CPS and represents the first report of a mannan CPS being expressed by these bacterial pathogens.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22221792     DOI： 10.1016/j.carres.2011.12.011

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  18 in total

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2.  pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells.

Authors:  Jennifer Chua; Jeffrey L Senft; Stephen J Lockett; Paul J Brett; Mary N Burtnick; David DeShazer; Arthur M Friedlander
Journal:  Infect Immun       Date:  2016-12-29       Impact factor: 3.441

3.  Burkholderia pseudomallei JW270 Is Lethal in the Madagascar Hissing Cockroach Infection Model and Can Be Utilized at Biosafety Level 2 to Identify Putative Virulence Factors.

Authors:  Jennifer Chua; Ethan Nguyenkhoa; Sherry Mou; Steven A Tobery; Arthur M Friedlander; David DeShazer
Journal:  Infect Immun       Date:  2022-07-11       Impact factor: 3.609

4.  Stereoselective Synthesis of β-d-Manno-heptopyranoside via Cs2CO3-Mediated Anomeric O-Alkylation: Synthesis of a Tetrasaccharide Repeat Unit of Bacillus thermoaerophilus Surface-Layer Glycoprotein.

Authors:  Shuai Meng; Ishani Lakshika Hettiarachchi; Bishwa Raj Bhetuwal; Prakash Thapa; Jianglong Zhu
Journal:  J Org Chem       Date:  2022-05-10       Impact factor: 4.198

5.  Contribution of murine IgG Fc regions to antibody binding to the capsule of Burkholderia pseudomallei.

Authors:  Michael J Dillon; Rachael A Loban; Dana E Reed; Peter Thorkildson; Kathryn J Pflughoeft; Sujata G Pandit; Paul J Brett; Mary N Burtnick; David P AuCoin
Journal:  Virulence       Date:  2016-04-20       Impact factor: 5.882

6.  Detailed structural analysis of the O-polysaccharide expressed by Burkholderia thailandensis E264.

Authors:  Christian Heiss; Mary N Burtnick; Ian Black; Parastoo Azadi; Paul J Brett
Journal:  Carbohydr Res       Date:  2012-10-11       Impact factor: 2.104

7.  Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei.

Authors:  Vichaya Suttisunhakul; Narisara Chantratita; Chanthiwa Wikraiphat; Vanaporn Wuthiekanun; Zakiya Douglas; Nicholas P J Day; Direk Limmathurotsakul; Paul J Brett; Mary N Burtnick
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8.  Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders.

Authors:  Mary N Burtnick; Christian Heiss; Rosemary A Roberts; Herbert P Schweizer; Parastoo Azadi; Paul J Brett
Journal:  Front Cell Infect Microbiol       Date:  2012-08-15       Impact factor: 5.293

9.  Capsule influences the deposition of critical complement C3 levels required for the killing of Burkholderia pseudomallei via NADPH-oxidase induction by human neutrophils.

Authors:  Michael E Woodman; Randall G Worth; R Mark Wooten
Journal:  PLoS One       Date:  2012-12-14       Impact factor: 3.240

10.  Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis.

Authors:  Raymond L Houghton; Dana E Reed; Mark A Hubbard; Michael J Dillon; Hongjing Chen; Bart J Currie; Mark Mayo; Derek S Sarovich; Vanessa Theobald; Direk Limmathurotsakul; Gumphol Wongsuvan; Narisara Chantratita; Sharon J Peacock; Alex R Hoffmaster; Brea Duval; Paul J Brett; Mary N Burtnick; David P Aucoin
Journal:  PLoS Negl Trop Dis       Date:  2014-03-20
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